Product References
Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury.
Antioxidants & redox signaling
Liu YT,Zhang H,Duan SB,Wang JW,Chen H,Zhan M,Zhang W,Li AM,Liu Y,Yang Y,Yang S
Mon Jan 01 00:00:00 EST 2024
IL-33/ST2 mediating systemic inflammation and neuroinflammation through NF-kB participated in the neurocognitive impairment in obstructive sleep apnea.
International immunopharmacology
Shen C,Liu X,Liu T,Ou Y,Ouyang R
Wed Feb 01 00:00:00 EST 2023
Slc6a13 Deficiency Attenuates Pasteurella multocida Infection-Induced Inflammation via Glycine-Inflammasome Signaling.
Journal of innate immunity
He F,Qiu Y,Wu X,Xia Y,Yang L,Wu C,Li P,Zhang R,Fang R,Li N,Peng Y
Tue Dec 26 00:00:00 EST 2023
miR-449a ameliorates acute rejection after liver transplantation via targeting procollagen-lysine1,2-oxoglutarate5-dioxygenase 1 in macrophages.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Cao ZR,Zheng WX,Jiang YX,Chai H,Gong JH,Zhao MJ,Yan P,Liu YY,Liu XY,Huang ZT,Yang H,Peng DD,Zong KZ,Wu ZJ
Wed Mar 01 00:00:00 EST 2023
Ge-Gen Decoction Exerts an Anti-Primary Dysmenorrhea Effect in Rats by Inactivating the HSP90/NLRP3/NF-κB/COX-2 Pathway.
Journal of inflammation research
Xie Y,Qian J
Tue Apr 25 00:00:00 EDT 2023
Corilagin ameliorates macrophages inflammation in atherosclerosis through TLR4-NFκB/MAPK pathway.
Heliyon
Meng D,Deng X,Wu Y,Wu J,Zhang Y,Zhang J,Zhao Y,Che Y
Thu Jun 01 00:00:00 EDT 2023
Gegen Qinlian standard decoction alleviated irinotecan-induced diarrhea via PI3K/AKT/NF-κB axis by network pharmacology prediction and experimental validation combination.
Chinese medicine
Chen J,Li M,Chen R,Xu Z,Yang X,Gu H,Zhang L,Fu C,Zhang J,Wu Y
Thu Apr 27 00:00:00 EDT 2023
Danzhi Jiangtang capsule reduces renal injury in rats with diabetes induced by high fat diet and streptozotocin downregulating toll-like receptor 4-nuclear factor-κB pathway and apoptosis.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Jing X,Zheng BI,Sihai W,Guoming S,Zhaohui F
Sat Apr 01 00:00:00 EDT 2023
Lipopolysaccharide exacerbates to the migration, invasion, and epithelial-mesenchymal transition of esophageal cancer cells by TLR4/NF-κB axis.
Environmental toxicology
Peng Z,Wan P,Deng Y,Shen W,Liu R
Mon May 01 00:00:00 EDT 2023
Astaxanthin suppresses oxidative stress and calcification in vertebral cartilage endplate via activating Nrf-2/HO-1 signaling pathway.
International immunopharmacology
Yang G,Liu X,Jing X,Wang J,Wang H,Chen F,Wang W,Shao Y,Cui X
Thu Jun 01 00:00:00 EDT 2023
Differences in p38-STAT3-S100A11 signaling after the administration of aristolochic acid I and IVa may account for the disparity in their nephrotoxicity.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Xian Z,Tian J,Zhao Y,Yi Y,Li C,Han J,Zhang Y,Wang Y,Wang L,Liu S,Pan C,Liu C,Wang D,Meng J,Tang X,Wang F,Liang A
Thu Jun 01 00:00:00 EDT 2023
Dual delivery of an NF-κB inhibitor and IL-10 through supramolecular hydrogels polarizes macrophages and promotes cardiac repair after myocardial infarction.
Acta biomaterialia
Wang D,Hu Y,Zhang L,Cai H,Wang Y,Zhang Y
Sat Jul 01 00:00:00 EDT 2023
SPON2 promotes the bone metastasis of lung adenocarcinoma via activation of the NF-κB signaling pathway.
Bone
Wu M,Kong D,Zhang Y
Wed Feb 01 00:00:00 EST 2023
Dexmedetomidine Protects against Airway Inflammation and Airway Remodeling in a Murine Model of Chronic Asthma through TLR4/NF-κB Signaling Pathway.
Mediators of inflammation
Zhou Y,Du X,Wang Q,Xiao S,Zhi J,Gao H,Yang D
Tue Feb 28 00:00:00 EST 2023
Anti-inflammatory and antioxidative effects of gallic acid on experimental dry eye: in vitro and in vivo studies.
Eye and vision (London, England)
Li K,Gong Q,Lu B,Huang K,Tong Y,Mutsvene TE,Lin M,Xu Z,Lu F,Li X,Hu L
Mon May 01 00:00:00 EDT 2023
Anti-inflammatory and antioxidative effects of gallic acid on experimental dry eye: in vitro and in vivo studies.
Eye and vision (London, England)
Li K,Gong Q,Lu B,Huang K,Tong Y,Mutsvene TE,Lin M,Xu Z,Lu F,Li X,Hu L
Mon May 01 00:00:00 EDT 2023
Baicalin ameliorates multidrug-resistant Pseudomonas aeruginosa induced pulmonary inflammation in rat via arginine biosynthesis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li L,Cui H,Zhang Y,Xie W,Lin Y,Guo Y,Huang T,Xue B,Guo W,Huang Z,Man T,Yu H,Zhai Z,Cheng M,Wang M,Lei H,Wang C
Thu Jun 01 00:00:00 EDT 2023
Baicalin ameliorates multidrug-resistant Pseudomonas aeruginosa induced pulmonary inflammation in rat via arginine biosynthesis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li L,Cui H,Zhang Y,Xie W,Lin Y,Guo Y,Huang T,Xue B,Guo W,Huang Z,Man T,Yu H,Zhai Z,Cheng M,Wang M,Lei H,Wang C
Thu Jun 01 00:00:00 EDT 2023
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Zoological research
Zhang MF,Wan SC,Chen WB,Yang DH,Liu WQ,Li BL,Aierken A,Du XM,Li YX,Wu WP,Yang XC,Wei YD,Li N,Peng S,Li XL,Li GP,Hua JL
Thu May 18 00:00:00 EDT 2023
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Zoological research
Zhang MF,Wan SC,Chen WB,Yang DH,Liu WQ,Li BL,Aierken A,Du XM,Li YX,Wu WP,Yang XC,Wei YD,Li N,Peng S,Li XL,Li GP,Hua JL
Thu May 18 00:00:00 EDT 2023
Hesperidin mitigates oxidative stress-induced ferroptosis in nucleus pulposus cells via Nrf2/NF-κB axis to protect intervertebral disc from degeneration.
Cell cycle (Georgetown, Tex.)
Zhu J,Sun R,Yan C,Sun K,Gao L,Zheng B,Shi J
Mon May 01 00:00:00 EDT 2023
Hesperidin mitigates oxidative stress-induced ferroptosis in nucleus pulposus cells via Nrf2/NF-κB axis to protect intervertebral disc from degeneration.
Cell cycle (Georgetown, Tex.)
Zhu J,Sun R,Yan C,Sun K,Gao L,Zheng B,Shi J
Mon May 01 00:00:00 EDT 2023
Exosome miR-3184-5p inhibits gastric cancer growth by targeting XBP1 to regulate the AKT, STAT3, and IRE1 signalling pathways.
Asia-Pacific journal of clinical oncology
Lin S,Que Y,Que C,Li F,Deng M,Xu D
Sat Apr 01 00:00:00 EDT 2023
CMTM3 protects the gastric epithelial cells from apoptosis and promotes IL-8 by stabilizing NEMO during Helicobacter pylori infection.
Gut pathogens
Zhang J,Ning J,Fu W,Shi Y,Zhang J,Ding S
Mon Feb 13 00:00:00 EST 2023
An HPK1 inhibitor enhanced the tumour response to anti-PD-1 immunotherapy in non-Hodgkin's lymphoma.
Clinical and experimental medicine
Yang L,Zhao Q,Chen T,Liu W,Qiu X,Chen J,Huang S,Huang R,Dong L
Wed Nov 01 00:00:00 EDT 2023
Palmitic acid combined with γ-interferon inhibits gastric cancer progression by modulating tumor-associated macrophages' polarization via the TLR4 pathway.
Journal of cancer research and clinical oncology
Zhang YY,Li J,Li F,Xue S,Xu QY,Zhang YQ,Feng L
Tue Aug 01 00:00:00 EDT 2023
Eugenol modulates the NOD1-NF-κB signaling pathway via targeting NF-κB protein in triple-negative breast cancer cells.
Frontiers in endocrinology
Shi X,Zhang W,Bao X,Liu X,Yang M,Yin C
Mon Mar 20 00:00:00 EDT 2023
Donkey Oil-Based Ketogenic Diet Prevents Tumor Progression by Regulating Intratumor Inflammation, Metastasis and Angiogenesis in CT26 Tumor-Bearing Mice.
Genes
Zhang H,Xie L,Zhang N,Qi X,Lu T,Xing J,Akhtar MF,Li L,Liu G
Sun Apr 30 00:00:00 EDT 2023
Role of Protein Tyrosine Phosphatase 1B Inhibitor in Early Brain Injury of Subarachnoid Hemorrhage in Mice.
Brain sciences
Zhang ZH,Zhou XM,Zhang X
Thu May 18 00:00:00 EDT 2023
Luteolin improves vasoconstriction function and survival of septic mice via AMPK/NF-κB pathway.
Heliyon
Liu B,Su H
Wed Feb 01 00:00:00 EST 2023
Protective Mechanism of Ethyl Gallate against Intestinal Ischemia-Reperfusion Injury in Mice by in Vivo and in Vitro Studies Based on Transcriptomics.
Chemistry & biodiversity
Fan S,Feng X,Li K,Li B,Diao Y
Sun Jan 01 00:00:00 EST 2023
DHX9 Strengthens Atherosclerosis Progression By Promoting Inflammation in Macrophages.
Inflammation
Huangfu N,Ma H,Tian M,Zhang J,Wang Y,Li Z,Chen X,Cui H
Sun Oct 01 00:00:00 EDT 2023
DHX9 Strengthens Atherosclerosis Progression By Promoting Inflammation in Macrophages.
Inflammation
Huangfu N,Ma H,Tian M,Zhang J,Wang Y,Li Z,Chen X,Cui H
Sun Oct 01 00:00:00 EDT 2023
DHX9 Strengthens Atherosclerosis Progression By Promoting Inflammation in Macrophages.
Inflammation
Huangfu N,Ma H,Tian M,Zhang J,Wang Y,Li Z,Chen X,Cui H
Sun Oct 01 00:00:00 EDT 2023
DHX9 Strengthens Atherosclerosis Progression By Promoting Inflammation in Macrophages.
Inflammation
Huangfu N,Ma H,Tian M,Zhang J,Wang Y,Li Z,Chen X,Cui H
Sun Oct 01 00:00:00 EDT 2023
Pi-Pa-Run-Fei-Tang alleviates lung injury by modulating IL-6/JAK2/STAT3/IL-17 and PI3K/AKT/NF-κB signaling pathway and balancing Th17 and Treg in murine model of OVA-induced asthma.
Journal of ethnopharmacology
Jie XL,Luo ZR,Yu J,Tong ZR,Li QQ,Wu JH,Tao Y,Feng PS,Lan JP,Wang P
Tue Dec 05 00:00:00 EST 2023
Huoxiang Zhengqi Oral Liquid Attenuates LPS-Induced Acute Lung Injury by Modulating Short-Chain Fatty Acid Levels and TLR4/NF-κB p65 Pathway.
BioMed research international
Tang R,Zhang J,Zhang R,Li X,Lv R,Nan H,Liu J,Zhao Z,He W,Wang L
Thu Mar 02 00:00:00 EST 2023
The NF-κB pathway plays a vital role in rat salivary gland atrophy model.
Heliyon
Yang Y,Zi Y,Conglin D,Chunmei Z,Liang H,Songlin W
Wed Mar 01 00:00:00 EST 2023
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.
Inflammation
Li K,Feng Z,Wang L,Ma X,Wang L,Liu K,Geng X,Peng C
Thu Jun 01 00:00:00 EDT 2023
The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB.
Cell reports
Fei X,Huang J,Li F,Wang Y,Shao Z,Dong L,Wu Y,Li B,Zhang X,Lv B,Zhao Y,Weng Q,Chen K,Zhang M,Yang S,Zhang C,Zhang M,Li W,Ying S,Sun Q,Chen Z,Shen H
Tue Jun 27 00:00:00 EDT 2023
Glioma-derived LRIG3 interacts with NETO2 in tumor-associated macrophages to modulate microenvironment and suppress tumor growth.
Cell death & disease
Li Y,Wang W,Hou X,Huang W,Zhang P,He Y,Wang B,Duan Q,Mao F,Guo D
Fri Jan 13 00:00:00 EST 2023
Normothermic ex vivo heart perfusion with NLRP3 inflammasome inhibitor Mcc950 treatment improves cardiac function of circulatory death hearts after transplantation.
Frontiers in cardiovascular medicine
Xu L,Zeng Z,Niu C,Liu D,Lin S,Liu X,Szabó G,Lu J,Zheng S,Zhou P
Tue Apr 04 00:00:00 EDT 2023
A systematic pharmacology-based in vivo study to reveal the effective mechanism of Yupingfeng in asthma treatment.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liu X,Yu Y,Wu Y,Luo A,Yang M,Li T,Li T,Mao B,Chen X,Fu J,Jiang H,Liu W
Thu Jun 01 00:00:00 EDT 2023
Anti-Inflammatory Effects of Allocryptopine via the Target on the CX3CL1-CX3CR1 axis/GNB5/AKT/NF-κB/Apoptosis in Dextran Sulfate-Induced Mice.
Biomedicines
Yang Y,Ding T,Xiao G,Huang J,Luo D,Yue M,Su Y,Jiang S,Zeng J,Liu Y
Sun Feb 05 00:00:00 EST 2023
METTL3-mediated m6A mRNA methylation regulates neutrophil activation through targeting TLR4 signaling.
Cell reports
Luo S,Liao C,Zhang L,Ling C,Zhang X,Xie P,Su G,Chen Z,Zhang L,Lai T,Tang J
Tue Mar 28 00:00:00 EDT 2023
Protective effect of inhibiting necroptosis on gentamicin-induced nephrotoxicity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Hu BF,Gong Q,Chen SQ,Yue L,Ma WX,Wang F,Feng XW,Wang JN,Li C,Liu MM,Wang XF,Meng XM,Li J,Wen JG
Thu Sep 01 00:00:00 EDT 2022
Mitochondrial transcription factor B2 overexpression increases M2 macrophage infiltration via cytosolic mitochondrial DNA-stimulated Interleukin-6 secretion in ovarian cancer.
Bioengineered
Wu W,Zhou S,Liu T,Liang D
Sun May 01 00:00:00 EDT 2022
Metabolomic Analysis Reveals that SPHK1 Promotes Oral Squamous Cell Carcinoma Progression through NF-κB Activation.
Annals of surgical oncology
Hou CX,Mao GY,Sun QW,Meng Y,Zhu QH,Tang YT,Han W,Sun NN,Song XM,Wang CX,Ye JH
Tue Nov 01 00:00:00 EDT 2022
Elevation of α-1,3 fucosylation promotes the binding ability of TNFR1 to TNF-α and contributes to osteoarthritic cartilage destruction and apoptosis.
Arthritis research & therapy
Yu H,Li M,Wen X,Yang J,Liang X,Li X,Bao X,Shu J,Ren X,Chen W,Li Z,Li Y
Fri Apr 29 00:00:00 EDT 2022
FNDC5 Causes Resistance to Sorafenib by Activating the PI3K/Akt/Nrf2 Pathway in Hepatocellular Carcinoma Cells.
Frontiers in oncology
Liu H,Zhao L,Wang M,Yang K,Jin Z,Zhao C,Shi G
Sat Apr 09 00:00:00 EDT 2022
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Frontiers in pharmacology
Shao Y,Sun L,Yang G,Wang W,Liu X,Du T,Chen F,Jing X,Cui X
Sat Oct 01 00:00:00 EDT 2022
Preconditioning with procyanidin B2 protects MAC-T cells against heat exposure-induced mitochondrial dysfunction and inflammation.
Molecular immunology
Wang H,Hao W,Yang L,Yan P,Wei S
Fri Jul 01 00:00:00 EDT 2022
RPS3 Promotes the Metastasis and Cisplatin Resistance of Adenoid Cystic Carcinoma.
Frontiers in oncology
Rui X,Huang Z,Chen R,Chen Y,Wang Y,Huang Z
Tue Jul 19 00:00:00 EDT 2022
Salubrinal protects against inflammatory response in macrophage and attenuates psoriasiform skin inflammation by antagonizing NF-κB signaling pathway.
Biochemical and biophysical research communications
Shangguan Y,Chen Y,Ma Y,Zhao Y,He Y,Li W
Sat Jan 22 00:00:00 EST 2022
Regulation of Cr(VI)-Induced Premature Senescence in L02 Hepatocytes by ROS-Ca2+-NF-κB Signaling.
Oxidative medicine and cellular longevity
Zhang Y,Yang G,Huang S,Yang X,Yuan F,Song Y,Liu S,Yu X
Thu Mar 17 00:00:00 EDT 2022
UHRF1 shapes both the trophoblast invasion and decidual macrophage differentiation in early pregnancy.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liu H,Wang LL,Xu QH,Wang J,Zhang YJ,Luo J,Liao AH
Fri Apr 01 00:00:00 EDT 2022
RP105 protects against ischemic and septic acute kidney injury via suppressing TLR4/NF-κB signaling pathways.
International immunopharmacology
Zhu J,Zhang Y,Shi L,Xia Y,Zha H,Li H,Song Z
Mon Aug 01 00:00:00 EDT 2022
Undescribed ecdysteroids and phenolic glycosides from the roots of Cyathula officinalis Kuan and their anti-inflammatory activity in LPS-induced RAW 264.7 macrophages in vitro.
Phytochemistry
Yang LF,Teng L,Huang YH,Tang M,Liao W,Fu Q
Fri Apr 01 00:00:00 EDT 2022
Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways.
Journal of ethnopharmacology
Shen Y,Teng L,Qu Y,Liu J,Zhu X,Chen S,Yang L,Huang Y,Song Q,Fu Q
Thu Feb 10 00:00:00 EST 2022
Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways.
Journal of ethnopharmacology
Shen Y,Teng L,Qu Y,Liu J,Zhu X,Chen S,Yang L,Huang Y,Song Q,Fu Q
Thu Feb 10 00:00:00 EST 2022
Rosuvastatin exerts cardioprotective effect in lipopolysaccharide-mediated injury of cardiomyocytes in an MG53-dependent manner.
BMC cardiovascular disorders
Zhuang J,Cheng G,Huang J,Guo H,Lai Y,Wang J,Shan Z,Zheng S
Wed Feb 23 00:00:00 EST 2022
Preventive effects of traditional Chinese medicine formula Huoxiangzhengqi against lipopolysaccharide-induced inflammatory response.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Gao M,Zou Z,Qiu Y,Sumayyah G,Jiang X,Su J,Duan X,Chen C,Qiu J
Sun May 01 00:00:00 EDT 2022
Procyanidin B2 ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
International immunopharmacology
Cai W,Zhang Y,Jin W,Wei S,Chen J,Zhong C,Zhong Y,Tu C,Peng H
Thu Dec 01 00:00:00 EST 2022
Procyanidin B2 ameliorates the progression of osteoarthritis: An in vitro and in vivo study.
International immunopharmacology
Cai W,Zhang Y,Jin W,Wei S,Chen J,Zhong C,Zhong Y,Tu C,Peng H
Thu Dec 01 00:00:00 EST 2022
3-(3-Hydroxyphenyl)propionic acid, a microbial metabolite of quercetin, inhibits monocyte binding to endothelial cells via modulating E-selectin expression.
Fitoterapia
Feng J,Ge C,Li W,Li R
Sat Jan 01 00:00:00 EST 2022
Neddylation Inhibition Causes Impaired Mouse Embryo Quality and Blastocyst Hatching Failure Through Elevated Oxidative Stress and Reduced IL-1β.
Frontiers in immunology
Yang G,Chen J,He Y,Luo H,Yuan H,Chen L,Huang L,Mao F,Hu S,Qian Y,Miao C,Feng R
Fri Jul 22 00:00:00 EDT 2022
TRIM62 silencing represses the proliferation and invasion and increases the chemosensitivity of hepatocellular carcinoma cells by affecting the NF-κB pathway.
Toxicology and applied pharmacology
Fan W,Liu X,Ren D
Wed Jun 15 00:00:00 EDT 2022
Network pharmacology and in vivo experiment-based strategy to investigate mechanisms of JingFangFuZiLiZhong formula for ulcerative colitis.
Annals of medicine
Wang M,Li J,Yin Y,Liu L,Wang Y,Qu Y,Hong Y,Ji S,Zhang T,Wang N,Liu J,Cao X,Zao X,Zhang S
Thu Dec 01 00:00:00 EST 2022
Normothermic Ex Vivo Heart Perfusion with Mesenchymal Stem Cell-Derived Conditioned Medium Improves Myocardial Tissue Protection in Rat Donation after Circulatory Death Hearts.
Stem cells international
Zeng Z,Xu L,Xu Y,Ruan Y,Liu D,Li J,Niu C,Zheng S,Zhou P,Xiao Z
Tue Nov 29 00:00:00 EST 2022
OPN Promotes Cell Proliferation and Invasion through NF-κB in Human Esophageal Squamous Cell Carcinoma.
Genetics research
Chen B,Liang S,Guo H,Xu L,Li J,Peng J
Wed Jan 11 00:00:00 EST 2023
AQP2 Promotes Astrocyte Activation by Modulating the TLR4/NFκB-p65 Pathway Following Intracerebral Hemorrhage.
Frontiers in immunology
Deng S,Chen X,Lei Q,Lu W
Fri Apr 08 00:00:00 EDT 2022
The ameliorative effect of melatonin on LPS-induced Sertoli cells inflammatory and tight junctions damage via suppression of the TLR4/MyD88/NF-κB signaling pathway in newborn calf.
Theriogenology
Feng R,Adeniran SO,Huang F,Li Y,Ma M,Zheng P,Zhang G
Tue Feb 01 00:00:00 EST 2022
The ameliorative effect of melatonin on LPS-induced Sertoli cells inflammatory and tight junctions damage via suppression of the TLR4/MyD88/NF-κB signaling pathway in newborn calf.
Theriogenology
Feng R,Adeniran SO,Huang F,Li Y,Ma M,Zheng P,Zhang G
Tue Feb 01 00:00:00 EST 2022
C1q/tumor necrosis factor-related protein 9 protects cultured chondrocytes from IL-1β-induced inflammatory injury by inhibiting NLRP3 inflammasome activation via the AdipoR1/AMPK axis.
Environmental toxicology
Wang B,Li Y,Hu S,Peng K
Fri Apr 01 00:00:00 EDT 2022
Succinate/IL-1β Signaling Axis Promotes the Inflammatory Progression of Endothelial and Exacerbates Atherosclerosis.
Frontiers in immunology
Xu J,Zheng Y,Zhao Y,Zhang Y,Li H,Zhang A,Wang X,Wang W,Hou Y,Wang J
Mon May 02 00:00:00 EDT 2022
Guizhi-Shaoyao-Zhimu decoction attenuates monosodium urate crystal-induced inflammation through inactivation of NF-κB and NLRP3 inflammasome.
Journal of ethnopharmacology
Zhou GQ,Chen G,Yang J,Qin WY,Ping J
Sun Jan 30 00:00:00 EST 2022
Treatment of Membranous Nephropathy by Disulfiram through Inhibition of Podocyte Pyroptosis.
Kidney diseases (Basel, Switzerland)
Lv D,Jiang S,Zhang M,Zhu X,Yang F,Wang H,Li S,Liu F,Zeng C,Qin W,Li L,Liu Z
Fri Jul 01 00:00:00 EDT 2022
Treatment of Membranous Nephropathy by Disulfiram through Inhibition of Podocyte Pyroptosis.
Kidney diseases (Basel, Switzerland)
Lv D,Jiang S,Zhang M,Zhu X,Yang F,Wang H,Li S,Liu F,Zeng C,Qin W,Li L,Liu Z
Fri Jul 01 00:00:00 EDT 2022
Treatment of Membranous Nephropathy by Disulfiram through Inhibition of Podocyte Pyroptosis.
Kidney diseases (Basel, Switzerland)
Lv D,Jiang S,Zhang M,Zhu X,Yang F,Wang H,Li S,Liu F,Zeng C,Qin W,Li L,Liu Z
Fri Jul 01 00:00:00 EDT 2022
Treatment of Membranous Nephropathy by Disulfiram through Inhibition of Podocyte Pyroptosis.
Kidney diseases (Basel, Switzerland)
Lv D,Jiang S,Zhang M,Zhu X,Yang F,Wang H,Li S,Liu F,Zeng C,Qin W,Li L,Liu Z
Fri Jul 01 00:00:00 EDT 2022
Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways.
Pharmacological research
Cai J,Liang J,Zhang Y,Shen L,Lin H,Hu T,Zhan S,Xie M,Liang S,Xian M,Wang S
Wed Jun 01 00:00:00 EDT 2022
Toll-like receptor 2 orchestrates a tumor suppressor response in non-small cell lung cancer.
Cell reports
Millar FR,Pennycuick A,Muir M,Quintanilla A,Hari P,Freyer E,Gautier P,Meynert A,Grimes G,Coll CS,Zdral S,Victorelli S,Teixeira VH,Connelly J,Passos JF,Ros MA,Wallace WAH,Frame MC,Sims AH,Boulter L,Janes SM,Wilkinson S,Acosta JC
Tue Nov 08 00:00:00 EST 2022
Oxybaphus himalaicus Mitigates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting TLR4/MD2 Complex Formation.
Antioxidants (Basel, Switzerland)
Zhan H,Pu Q,Long X,Lu W,Wang G,Meng F,Liao Z,Lan X,Chen M
Tue Nov 22 00:00:00 EST 2022
Oxybaphus himalaicus Mitigates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting TLR4/MD2 Complex Formation.
Antioxidants (Basel, Switzerland)
Zhan H,Pu Q,Long X,Lu W,Wang G,Meng F,Liao Z,Lan X,Chen M
Tue Nov 22 00:00:00 EST 2022
Tripartite motif-containing 25 facilitates immunosuppression and inhibits apoptosis of glioma via activating NF-κB.
Experimental biology and medicine (Maywood, N.J.)
Ge MX,Shi YK,Liu D
Thu Sep 01 00:00:00 EDT 2022
Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer's disease.
Journal of neuroinflammation
Dong Y,Yu H,Li X,Bian K,Zheng Y,Dai M,Feng X,Sun Y,He Y,Yu B,Zhang H,Wu J,Yu X,Wu H,Kong W
Mon Aug 15 00:00:00 EDT 2022
Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer's disease.
Journal of neuroinflammation
Dong Y,Yu H,Li X,Bian K,Zheng Y,Dai M,Feng X,Sun Y,He Y,Yu B,Zhang H,Wu J,Yu X,Wu H,Kong W
Mon Aug 15 00:00:00 EDT 2022
Chronic intermittent hypoxia induces the pyroptosis of renal tubular epithelial cells by activating the NLRP3 inflammasome.
Bioengineered
Bai C,Zhu Y,Dong Q,Zhang Y
Tue Mar 01 00:00:00 EST 2022
Hydrogen sulfide ameliorated preeclampsia via suppression of toll-like receptor 4-activated inflammation in the rostral ventrolateral medulla of rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Du J,Wang P,Gou Q,Jin S,Xue H,Li D,Tian D,Sun J,Zhang X,Teng X,Wu Y
Wed Jun 01 00:00:00 EDT 2022
Free and Bound Phenolics of Laird Lentil (Lens culinaris) Hulls and the Anti-inflammatory Activity of their Digestive Products via Crosstalk between NF-κB and Keap1-Nrf2 Signaling Pathways in HT-29 Cells.
Journal of agricultural and food chemistry
Guo F,Peng L,Xiong H,Wang J,Tsao R,Peng X,Jiang L,Sun Y
Wed Oct 19 00:00:00 EDT 2022
Free and Bound Phenolics of Laird Lentil (Lens culinaris) Hulls and the Anti-inflammatory Activity of their Digestive Products via Crosstalk between NF-κB and Keap1-Nrf2 Signaling Pathways in HT-29 Cells.
Journal of agricultural and food chemistry
Guo F,Peng L,Xiong H,Wang J,Tsao R,Peng X,Jiang L,Sun Y
Wed Oct 19 00:00:00 EDT 2022
Systematic evaluation of the anti-tumor effect of Phellinus linteus polysaccharide in thyroid carcinoma in vitro.
Molecular biology reports
Yu K,Tan Z,Xin Y
Fri Apr 01 00:00:00 EDT 2022
PRKAR2A-derived circular RNAs promote the malignant transformation of colitis and distinguish patients with colitis-associated colorectal cancer.
Clinical and translational medicine
Wan D,Wang S,Xu Z,Zan X,Liu F,Han Y,Jiang M,Wu A,Zhi Q
Tue Feb 01 00:00:00 EST 2022
l-Arginine prevents 4-hydroxy-2-nonenal accumulation and depresses inflammation via inhibiting NF-κB activation.
Journal of biochemical and molecular toxicology
Liang M,Wang Z,Li H,Liu B,Yang L
Mon Aug 01 00:00:00 EDT 2022
Thiram induces myocardial oxidative damage and apoptosis in broilers via interfering their cardiac metabolism.
Ecotoxicology and environmental safety
Mo Q,Kulyar MF,Ding Y,Zhang Y,Pan H,Li J
Thu Dec 01 00:00:00 EST 2022
New Baitouweng decoction combined with fecal microbiota transplantation alleviates DSS-induced colitis in rats by regulating gut microbiota metabolic homeostasis and the STAT3/NF-κB signaling pathway.
BMC complementary medicine and therapies
Gu X,Miao Z,Wang Y,Yang Y,Yang T,Xu Y
Thu Nov 24 00:00:00 EST 2022
Perilipin 5 protects against oxygen-glucose deprivation/reoxygenation-elicited neuronal damage by inhibiting oxidative stress and inflammatory injury via the Akt-GSK-3β-Nrf2 pathway.
International immunopharmacology
Huo K,Ma KG,Guo QY,Duan P,Xu J
Fri Jul 01 00:00:00 EDT 2022
Reduced inhibition underlies early life LPS exposure induced-cognitive impairment: Prevention by environmental enrichment.
International immunopharmacology
Wu XM,Ji MH,Yin XY,Gu HW,Zhu TT,Wang RZ,Yang JJ,Shen JC
Fri Jul 01 00:00:00 EDT 2022
Effect of Lactobacillus with Feruloyl Esterase-Producing Ability on Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice.
Journal of agricultural and food chemistry
Shen D,Ma S,Li X,Lu Y
Wed Nov 30 00:00:00 EST 2022
Prohibitin Protects Pulmonary Microvascular Endothelial Cells Against Cigarette Smoke Extract-Induced Cell Apoptosis and Inflammation.
International journal of chronic obstructive pulmonary disease
Peng Y,Cheng W,Duan J,Zhao Y,Zhou Z,Zhou A,Deng M,Peng H,Ouyang R,Chen Y,Chen P
Wed Apr 06 00:00:00 EDT 2022
FumDSB can alleviate the inflammatory response induced by fumonisin B1 in growing pigs.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment
Liu Q,Huang L,Cui Z,Qiao B,Li F,Wang C
Thu Sep 01 00:00:00 EDT 2022
Empagliflozin inhibits macrophage inflammation through AMPK signaling pathway and plays an anti-atherosclerosis role.
International journal of cardiology
Fu J,Xu H,Wu F,Tu Q,Dong X,Xie H,Cao Z
Tue Nov 15 00:00:00 EST 2022
Dihydroartemisinin attenuates osteoclast formation and bone resorption via inhibiting the NF‑κB, MAPK and NFATc1 signaling pathways and alleviates osteoarthritis.
International journal of molecular medicine
Ding D,Yan J,Feng G,Zhou Y,Ma L,Jin Q
Sat Jan 01 00:00:00 EST 2022
Upregulation of BRD7 protects podocytes against high glucose-induced apoptosis by enhancing Nrf2 in a GSK-3β-dependent manner.
Tissue & cell
Yu X,Jiang N,Li J,Li X,He S
Wed Jun 01 00:00:00 EDT 2022
Phenolic Acids from Fructus Chebulae Immaturus Alleviate Intestinal Ischemia-Reperfusion Injury in Mice through the PPARα/NF-κB Pathway.
Molecules (Basel, Switzerland)
Liu J,Li B,Liu J,Qiu F,Diao Y,Lei Y,Liu J,Zhang W
Tue Aug 16 00:00:00 EDT 2022
PBK drives PARP inhibitor resistance through the TRIM37/NFκB axis in ovarian cancer.
Experimental & molecular medicine
Ma H,Qi G,Han F,Peng J,Yuan C,Kong B
Fri Jul 01 00:00:00 EDT 2022
Scutellarein protects against cardiac hypertrophy via suppressing TRAF2/NF-κB signaling pathway.
Molecular biology reports
Shi X,Hu Y,Jiang Y,Wu J,Zhang C,Zhang J,Wu S,Wu Y,Dong W,Li J
Tue Mar 01 00:00:00 EST 2022
CCK regulates osteogenic differentiation through TNFα/NF-κB in peri-implantitis.
The Journal of international medical research
Chou L,Chang Y,Lan K,Liu M,Lu Y,Li X,Li P,Xu Y
Thu Dec 01 00:00:00 EST 2022
Protective Effects and Mechanisms of Yinchen Linggui Zhugan Decoction in HFD-Induced Nonalcoholic Fatty Liver Disease Rats Based on Network Pharmacology and Experimental Verification.
Frontiers in pharmacology
Jiang H,Mao T,Liu Y,Tan X,Sun Z,Cheng Y,Han X,Zhang Y,Wang J,Shi L,Guo Y,Li J,Han H
Sat Jul 16 00:00:00 EDT 2022
Edaravone dexborneol provides neuroprotective benefits by suppressing NLRP3 inflammasome-induced microglial pyroptosis in experimental ischemic stroke.
International immunopharmacology
Hu R,Liang J,Ding L,Zhang W,Liu X,Song B,Xu Y
Thu Dec 01 00:00:00 EST 2022
Suppression of Cutibacterium acnes-Mediated Inflammatory Reactions by Fibroblast Growth Factor 21 in Skin.
International journal of molecular sciences
Yu Y,Shen Y,Zhang S,Wang N,Luo L,Zhu X,Xu X,Cong W,Jin L,Zhu Z
Fri Mar 25 00:00:00 EDT 2022
Effects of Uremic Clearance Granules on p38 MAPK/NF-κB Signaling Pathway, Microbial and Metabolic Profiles in End-Stage Renal Disease Rats Receiving Peritoneal Dialysis.
Drug design, development and therapy
Li X,Zheng J,Wang J,Tang X,Zhang F,Liu S,Liao Y,Chen X,Xie W,Tang Y
Thu Aug 11 00:00:00 EDT 2022
Panax notoginseng saponins alleviate damage to the intestinal barrier and regulate levels of intestinal microbes in a rat model of chronic kidney disease.
Renal failure
Xie J,Ma X,Zheng Y,Mao N,Ren S,Fan J
Thu Dec 01 00:00:00 EST 2022
A Novel Rat Model of Dry Eye Induced by Aerosol Exposure of Particulate Matter.
Investigative ophthalmology & visual science
Mu N,Wang H,Chen D,Wang F,Ji L,Zhang C,Li M,Lu P
Mon Jan 03 00:00:00 EST 2022
Resveratrol affects the expression of uric acid transporter by improving inflammation.
Molecular medicine reports
Zhang X,Nie Q,Zhang Z,Zhao J,Zhang F,Wang C,Wang X,Song G
Sun Aug 01 00:00:00 EDT 2021
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
Journal of cellular and molecular medicine
Ma L,Li C,Lian S,Xu B,Lv H,Liu Y,Lu J,Ji H,Li S,Guo J,Yang H
Sun Aug 01 00:00:00 EDT 2021
Selective STAT3 Inhibitor Alantolactone Ameliorates Osteoarthritis via Regulating Chondrocyte Autophagy and Cartilage Homeostasis.
Frontiers in pharmacology
Pei W,Huang X,Ni B,Zhang R,Niu G,You H
Sat Oct 16 00:00:00 EDT 2021
Selective STAT3 Inhibitor Alantolactone Ameliorates Osteoarthritis via Regulating Chondrocyte Autophagy and Cartilage Homeostasis.
Frontiers in pharmacology
Pei W,Huang X,Ni B,Zhang R,Niu G,You H
Sat Oct 16 00:00:00 EDT 2021
Live Combined B. subtilis and E. faecium Alleviate Liver Inflammation, Improve Intestinal Barrier Function, and Modulate Gut Microbiota in Mice with Non-Alcoholic Fatty Liver Disease.
Medical science monitor : international medical journal of experimental and clinical research
Jiang J,Xiong J,Ni J,Chen C,Wang K
Sun Sep 05 00:00:00 EDT 2021
Protective effects of curcumin against rat intestinal inflammation‑related motility disorders.
Molecular medicine reports
Yao Y,Luo R,Xiong S,Zhang C,Zhang Y
Sat May 01 00:00:00 EDT 2021
Prussian blue nanozyme-mediated nanoscavenger ameliorates acute pancreatitis via inhibiting TLRs/NF-κB signaling pathway.
Theranostics
Xie X,Zhao J,Gao W,Chen J,Hu B,Cai X,Zheng Y
Tue Jul 27 00:00:00 EDT 2021
Metformin attenuates osteoclast-mediated abnormal subchondral bone remodeling and alleviates osteoarthritis via AMPK/NF-κB/ERK signaling pathway.
PloS one
Guo H,Ding D,Wang L,Yan J,Ma L,Jin Q
Mon Jan 10 00:00:00 EST 2022
Metformin attenuates osteoclast-mediated abnormal subchondral bone remodeling and alleviates osteoarthritis via AMPK/NF-κB/ERK signaling pathway.
PloS one
Guo H,Ding D,Wang L,Yan J,Ma L,Jin Q
Mon Jan 10 00:00:00 EST 2022
FNDC5 induces M2 macrophage polarization and promotes hepatocellular carcinoma cell growth by affecting the PPARγ/NF-κB/NLRP3 pathway.
Biochemical and biophysical research communications
Liu H,Wang M,Jin Z,Sun D,Zhu T,Liu X,Tan X,Shi G
Fri Dec 10 00:00:00 EST 2021
Genistein ameliorates inflammation and insulin resistance through mediation of gut microbiota composition in type 2 diabetic mice.
European journal of nutrition
Yang R,Jia Q,Mehmood S,Ma S,Liu X
Tue Jun 01 00:00:00 EDT 2021
Pristimerin reduces dextran sulfate sodium-induced colitis in mice by inhibiting microRNA-155.
International immunopharmacology
Tian M,Peng S,Wang S,Li X,Li H,Shen L
Sat May 01 00:00:00 EDT 2021
The Anti-Inflammatory Effect of a Combination of Five Compounds From Five Chinese Herbal Medicines Used in the Treatment of COPD.
Frontiers in pharmacology
Li J,Zhao P,Tian Y,Li K,Zhang L,Guan Q,Mei X,Qin Y
Wed Nov 17 00:00:00 EST 2021
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
Ecotoxicology and environmental safety
Liu C,Qu J,Wu M,Huang X,Li L
Wed Dec 01 00:00:00 EST 2021
Cypermethrin triggers YY1-mediated testosterone biosynthesis suppression.
Ecotoxicology and environmental safety
Liu C,Qu J,Wu M,Huang X,Li L
Wed Dec 01 00:00:00 EST 2021
The probiotic effects of AB23A on high-fat-diet-induced non-alcoholic fatty liver disease in mice may be associated with suppressing the serum levels of lipopolysaccharides and branched-chain amino acids.
Archives of biochemistry and biophysics
Xia F,Xiang S,Chen Z,Song L,Li Y,Liao Z,Ge B,Zhou B
Wed Dec 15 00:00:00 EST 2021
Normothermic ex vivo Heart Perfusion Combined With Melatonin Enhances Myocardial Protection in Rat Donation After Circulatory Death Hearts via Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis.
Frontiers in cell and developmental biology
Lu J,Xu L,Zeng Z,Xue C,Li J,Chen X,Zhou P,Lin S,Liao Y,Du X,Yang R,Zheng S
Tue Apr 26 00:00:00 EDT 2022
Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Peng X,Hao M,Zhao Y,Cai Y,Chen X,Chen H,Zhang Y,Dong L,Liu X,Ding C,Liu W,Yang M,Luo Y
Wed Dec 01 00:00:00 EST 2021
Paeoniflorin Suppresses TBHP-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells via the Nrf2/HO-1 Signaling Pathway and Improves Skin Flap Survival.
Frontiers in pharmacology
Jiang J,Dong C,Zhai L,Lou J,Jin J,Cheng S,Chen Z,Guo X,Lin D,Ding J,Gao W
Tue Nov 23 00:00:00 EST 2021
Paeoniflorin Suppresses TBHP-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells via the Nrf2/HO-1 Signaling Pathway and Improves Skin Flap Survival.
Frontiers in pharmacology
Jiang J,Dong C,Zhai L,Lou J,Jin J,Cheng S,Chen Z,Guo X,Lin D,Ding J,Gao W
Tue Nov 23 00:00:00 EST 2021
HSP90 acts as a senomorphic target in senescent retinal pigmental epithelial cells.
Aging
Chen DD,Peng X,Wang Y,Jiang M,Xue M,Shang G,Liu X,Jia X,Liu B,Lu Y,Mu H,Zhang F,Hu Y
Wed Sep 08 00:00:00 EDT 2021
Aloe-emodin prevents nerve injury and neuroinflammation caused by ischemic stroke via the PI3K/AKT/mTOR and NF-κB pathway.
Food & function
Xian M,Cai J,Zheng K,Liu Q,Liu Y,Lin H,Liang S,Wang S
Tue Sep 07 00:00:00 EDT 2021
Naringin Exerts Therapeutic Effects on Mice Colitis: A Study Based on Transcriptomics Combined With Functional Experiments.
Frontiers in pharmacology
Dong J,Chen Y,Yang F,Zhang W,Wei K,Xiong Y,Wang L,Zhou Z,Li C,Wang J,Chen D
Sat Sep 11 00:00:00 EDT 2021
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Scientific reports
Zhao Y,Liu X,Zheng Y,Liu W,Ding C
Mon Oct 18 00:00:00 EDT 2021
Gas6/TAM Signalling Negatively Regulates Inflammatory Induction of GM-CSF in Mouse Brain Microglia.
Cells
Gilchrist SE,Pennelli GM,Hafizi S
Wed Nov 24 00:00:00 EST 2021
Rosiglitazone alleviates lipopolysaccharide-induced inflammation in RAW264.7 cells via inhibition of NF-κB and in a PPARγ-dependent manner.
Experimental and therapeutic medicine
Zhou JP,Yang XN,Song Y,Zhou F,Liu JJ,Hu YQ,Chen LG
Thu Jul 01 00:00:00 EDT 2021
DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma.
Journal of experimental & clinical cancer research : CR
Zhu B,Chen JJ,Feng Y,Yang JL,Huang H,Chung WY,Hu YL,Xue WJ
Mon Nov 08 00:00:00 EST 2021
DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma.
Journal of experimental & clinical cancer research : CR
Zhu B,Chen JJ,Feng Y,Yang JL,Huang H,Chung WY,Hu YL,Xue WJ
Mon Nov 08 00:00:00 EST 2021
DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma.
Journal of experimental & clinical cancer research : CR
Zhu B,Chen JJ,Feng Y,Yang JL,Huang H,Chung WY,Hu YL,Xue WJ
Mon Nov 08 00:00:00 EST 2021
Platycodon grandiflorum extract attenuates lipopolysaccharide-induced acute lung injury via TLR4/NF-κBp65 pathway in rats.
Pakistan journal of pharmaceutical sciences
Si-Cong L,Chaoqin R,Ge L,Xu-Ting L,Jin-Liang L,Bin W,Min Z,Wei H,Liang C,Xue G
Mon Nov 01 00:00:00 EDT 2021
Myricetin ameliorates ox-LDL-induced HUVECs apoptosis and inflammation via lncRNA GAS5 upregulating the expression of miR-29a-3p.
Scientific reports
Bai Y,Liu X,Chen Q,Chen T,Jiang N,Guo Z
Mon Oct 04 00:00:00 EDT 2021
Quercitrin Rapidly Alleviated Depression-like Behaviors in Lipopolysaccharide-Treated Mice: The Involvement of PI3K/AKT/NF-κB Signaling Suppression and CREB/BDNF Signaling Restoration in the Hippocampus.
ACS chemical neuroscience
Sun Y,Zhang H,Wu Z,Yu X,Yin Y,Qian S,Wang Z,Huang J,Wang W,Liu T,Xue W,Chen G
Wed Sep 15 00:00:00 EDT 2021
Butyrate functions in concert with myeloid-derived suppressor cells recruited by CCR9 to alleviate DSS-induced murine colitis.
International immunopharmacology
Xiao T,Zhang P,Feng T,Lu K,Wang X,Zhou S,Qiang Y
Fri Oct 01 00:00:00 EDT 2021
Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia-reperfusion.
Journal of neuroinflammation
Liu DD,Luo P,Gu L,Zhang Q,Gao P,Zhu Y,Chen X,Guo Q,Zhang J,Ma N,Wang J
Mon Aug 09 00:00:00 EDT 2021
Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia-reperfusion.
Journal of neuroinflammation
Liu DD,Luo P,Gu L,Zhang Q,Gao P,Zhu Y,Chen X,Guo Q,Zhang J,Ma N,Wang J
Mon Aug 09 00:00:00 EDT 2021
Curcumin inhibits classical swine fever virus replication by interfering with lipid metabolism.
Veterinary microbiology
Gao Y,Hu JH,Liang XD,Chen J,Liu CC,Liu YY,Cheng Y,Go YY,Zhou B
Sun Aug 01 00:00:00 EDT 2021
Formosanin C attenuates lipopolysaccharide-induced inflammation through nuclear factor-κB inhibition in macrophages.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Yin L,Shi C,Zhang Z,Wang W,Li M
Wed Sep 01 00:00:00 EDT 2021
Neutrophil elastase promotes neointimal hyperplasia by targeting toll-like receptor 4 (TLR4)-NF-κB signalling.
British journal of pharmacology
Yang M,Chen Q,Mei L,Wen G,An W,Zhou X,Niu K,Liu C,Ren M,Sun K,Xiao Q,Zhang L
Fri Oct 01 00:00:00 EDT 2021
Ginsenoside CK Inhibits Hypoxia-Induced Epithelial-Mesenchymal Transformation through the HIF-1α/NF-κB Feedback Pathway in Hepatocellular Carcinoma.
Foods (Basel, Switzerland)
Zhang J,Ma X,Fan D
Wed May 26 00:00:00 EDT 2021
Ginsenoside CK Inhibits Hypoxia-Induced Epithelial-Mesenchymal Transformation through the HIF-1α/NF-κB Feedback Pathway in Hepatocellular Carcinoma.
Foods (Basel, Switzerland)
Zhang J,Ma X,Fan D
Wed May 26 00:00:00 EDT 2021
The protective role of Zingerone in a murine asthma model via activation of the AMPK/Nrf2/HO-1 pathway.
Food & function
Zhu Y,Wang C,Luo J,Hua S,Li D,Peng L,Liu H,Song L
Wed Apr 07 00:00:00 EDT 2021
The protective role of Zingerone in a murine asthma model via activation of the AMPK/Nrf2/HO-1 pathway.
Food & function
Zhu Y,Wang C,Luo J,Hua S,Li D,Peng L,Liu H,Song L
Wed Apr 07 00:00:00 EDT 2021
Hyaluronic acid/polyethyleneimine nanoparticles loaded with copper ion and disulfiram for esophageal cancer.
Carbohydrate polymers
Xu R,Zhang K,Liang J,Gao F,Li J,Guan F
Tue Jun 01 00:00:00 EDT 2021
MiR-1224-5p attenuates polycystic ovary syndrome through inhibiting NOD-like receptor protein 3 inflammasome activation via targeting Forkhead box O 1.
Bioengineered
Li Y,Yao N,Gao Y,Wang Y,Bai L,Xu J,Wang H
Wed Dec 01 00:00:00 EST 2021
Activation of Adenosine A1 Receptor in Ischemic Stroke: Neuroprotection by Tetrahydroxy Stilbene Glycoside as an Agonist.
Antioxidants (Basel, Switzerland)
Ruan L,Li G,Zhao W,Meng H,Zheng Q,Wang J
Mon Jul 12 00:00:00 EDT 2021
Chronic developmental exposure to low-dose ([C8mim][PF6]) induces neurotoxicity and behavioural abnormalities in rats.
Ecotoxicology and environmental safety
Su X,Li W,Li Z,Liu K,Song M,Shao M,Lv L,Chang X
Wed Dec 01 00:00:00 EST 2021
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Chemico-biological interactions
Lu Y,Hao R,Hu Y,Wei Y,Xie Y,Shen Y,Rui Q,Yu G
Fri Oct 01 00:00:00 EDT 2021
CircEpc1 Promotes Ricin Toxin-Induced Inflammation via Activation of NF-κB and MAPK Signaling Pathways by Sponging miR-5114.
Frontiers in pharmacology
Dong M,Zhang X,Yu H,Wang Y,Chang Y,Sun C,Zhang J,Zhao N,Yu K,Sun G,Zhao G,Xu N,Liu W
Wed Nov 10 00:00:00 EST 2021
Enriched Environment Attenuates Pyroptosis to Improve Functional Recovery After Cerebral Ischemia/Reperfusion Injury.
Frontiers in aging neuroscience
Liu J,Zheng J,Xu Y,Cao W,Wang J,Wang B,Zhao L,Zhang X,Liao W
Fri Oct 15 00:00:00 EDT 2021
1β-Hydroxyalantolactone from Inulae Flos alleviated the progression of pulmonary fibrosis via inhibiting JNK/FOXO1/NF-κB pathway.
International immunopharmacology
Yu B,Jin XQ,Yu WY,Dong YY,Ying HZ,Yu CH
Wed Dec 01 00:00:00 EST 2021
MicroRNA Bta-miR-24-3p Suppressed Galectin-9 Expression through TLR4/NF-ĸB Signaling Pathway in LPS-Stimulated Bovine Endometrial Epithelial Cells.
Cells
Oladejo AO,Li Y,Shen W,Imam BH,Wu X,Yang J,Ma X,Lv Y,Jiang W,Ding X,Wang S,Yan Z
Thu Nov 25 00:00:00 EST 2021
MicroRNA Bta-miR-24-3p Suppressed Galectin-9 Expression through TLR4/NF-ĸB Signaling Pathway in LPS-Stimulated Bovine Endometrial Epithelial Cells.
Cells
Oladejo AO,Li Y,Shen W,Imam BH,Wu X,Yang J,Ma X,Lv Y,Jiang W,Ding X,Wang S,Yan Z
Thu Nov 25 00:00:00 EST 2021
Immunomodulation effects of polyphenols from thinned peach treated by different drying methods on RAW264.7 cells through the NF-κB and Nrf2 pathways.
Food chemistry
Guo C,Bi J,Li X,Lyu J,Liu X,Wu X,Liu J
Mon Mar 15 00:00:00 EDT 2021
Isorhamnetin Enhances the Radiosensitivity of A549 Cells Through Interleukin-13 and the NF-κB Signaling Pathway.
Frontiers in pharmacology
Du Y,Jia C,Liu Y,Li Y,Wang J,Sun K
Fri Feb 12 00:00:00 EST 2021
Xanthatin alleviates airway inflammation in asthmatic mice by regulating the STAT3/NF-κB signaling pathway.
Respiratory physiology & neurobiology
Chang J,Gao J,Lou L,Chu H,Li P,Chen T,Gao F
Thu Oct 01 00:00:00 EDT 2020
Interleukin-1β in hypothalamic paraventricular nucleus mediates excitatory renal reflex.
Pflugers Archiv : European journal of physiology
Zheng F,Ye C,Wan GW,Zhou B,Tong Y,Lei JZ,Chen Q,Li YH,Kang YM,Zhu GQ
Sun Nov 01 00:00:00 EDT 2020
Astaxanthin attenuates oxidative stress and immune impairment in D-galactose-induced aging in rats by activating the Nrf2/Keap1 pathway and suppressing the NF-κB pathway.
Food & function
Chen Z,Xiao J,Liu H,Yao K,Hou X,Cao Y,Liu X
Wed Sep 23 00:00:00 EDT 2020
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
Oncology research
Wei W,Ma XD,Jiang GM,Shi B,Zhong W,Sun CL,Zhao L,Hou YJ,Wang H
Tue Sep 01 00:00:00 EDT 2020
Cross-regulation by TLR4 and T cell Ig mucin-3 determines severity of liver injury in a CCl4-induced mouse model.
Scandinavian journal of immunology
Zhao L,Liang J,Rao W,Cui M,Ren S,Zhang L,Xu D,Han Q,Zang YJ,Zhang B
Wed Apr 01 00:00:00 EDT 2020
A chondroprotective effect of moracin on IL-1β-induced primary rat chondrocytes and an osteoarthritis rat model through Nrf2/HO-1 and NF-κB axes.
Food & function
Zhou S,Shi J,Wen H,Xie W,Han X,Li H
Wed Sep 23 00:00:00 EDT 2020
A chondroprotective effect of moracin on IL-1β-induced primary rat chondrocytes and an osteoarthritis rat model through Nrf2/HO-1 and NF-κB axes.
Food & function
Zhou S,Shi J,Wen H,Xie W,Han X,Li H
Wed Sep 23 00:00:00 EDT 2020
Indoxyl sulfate promotes osteogenic differentiation of vascular smooth muscle cells by miR-155-5p-dependent downregulation of matrix Gla protein via ROS/NF-κB signaling.
Experimental cell research
He X,Wang Z,Wei L,Cheng X,Chen L,Gao F,Jiang H
Tue Dec 01 00:00:00 EST 2020
Indoxyl sulfate promotes osteogenic differentiation of vascular smooth muscle cells by miR-155-5p-dependent downregulation of matrix Gla protein via ROS/NF-κB signaling.
Experimental cell research
He X,Wang Z,Wei L,Cheng X,Chen L,Gao F,Jiang H
Tue Dec 01 00:00:00 EST 2020
Indoxyl sulfate promotes osteogenic differentiation of vascular smooth muscle cells by miR-155-5p-dependent downregulation of matrix Gla protein via ROS/NF-κB signaling.
Experimental cell research
He X,Wang Z,Wei L,Cheng X,Chen L,Gao F,Jiang H
Tue Dec 01 00:00:00 EST 2020
Indoxyl sulfate promotes osteogenic differentiation of vascular smooth muscle cells by miR-155-5p-dependent downregulation of matrix Gla protein via ROS/NF-κB signaling.
Experimental cell research
He X,Wang Z,Wei L,Cheng X,Chen L,Gao F,Jiang H
Tue Dec 01 00:00:00 EST 2020
Silencing of lncRNA MIAT alleviates LPS-induced pneumonia via regulating miR-147a/NKAP/NF-κB axis.
Aging
Liu M,Li W,Song F,Zhang L,Sun X
Wed Dec 09 00:00:00 EST 2020
RNA-Binding Protein HuR Suppresses Inflammation and Promotes Extracellular Matrix Homeostasis via NKRF in Intervertebral Disc Degeneration.
Frontiers in cell and developmental biology
Shao Z,Tu Z,Shi Y,Li S,Wu A,Wu Y,Tian N,Sun L,Pan Z,Chen L,Gao W,Zhou Y,Wang X,Zhang X
Fri Dec 18 00:00:00 EST 2020
Negative Regulation of Tec Kinase Alleviates LPS-Induced Acute Kidney Injury in Mice via theTLR4/NF-κB Signaling Pathway.
BioMed research international
Zhang W,Zhou P,Jiang X,Fan Z,Xu X,Wang F
Wed Apr 28 00:00:00 EDT 2021
Ectopic Expression of miR-532-3p Suppresses Bone Metastasis of Prostate Cancer Cells via Inactivating NF-κB Signaling.
Molecular therapy oncolytics
Wa Q,Zou C,Lin Z,Huang S,Peng X,Yang C,Ren D,Xu D,Guo Y,Liao Z,Wang B,Hu H,Huang S,He P
Fri Jun 26 00:00:00 EDT 2020
Physicochemical characterization of polysaccharide from the leaf of Dendrobium officinale and effect on LPS induced damage in GES-1 cell.
International journal of biological macromolecules
Yang K,Lu T,Zhan L,Zhou C,Zhang N,Lei S,Wang Y,Yang J,Yan M,Lv G,Chen S
Wed Apr 15 00:00:00 EDT 2020
Neutrophil extracellular traps mediate the crosstalk between glioma progression and the tumor microenvironment the HMGB1/RAGE/IL-8 axis.
Cancer biology & medicine
Zha C,Meng X,Li L,Mi S,Qian D,Li Z,Wu P,Hu S,Zhao S,Cai J,Liu Y
Sat Feb 15 00:00:00 EST 2020
Anti-inflammatory and analgesic activities of indigo through regulating the IKKβ/IκB/NF-κB pathway in mice.
Food & function
Liu N,Zhang GX,Niu YT,Wang Q,Zheng J,Yang JM,Sun T,Niu JG,Yu JQ
Thu Oct 01 00:00:00 EDT 2020
Magnesium isoglycyrrhizinate ameliorates fructose-induced podocyte apoptosis through downregulation of miR-193a to increase WT1.
Biochemical pharmacology
Li TS,Chen L,Wang SC,Yang YZ,Xu HJ,Gu HM,Zhao XJ,Dong P,Pan Y,Shang ZQ,Zhang XQ,Kong LD
Thu Aug 01 00:00:00 EDT 2019
The therapeutic effect of verapamil in lipopolysaccharide-induced acute lung injury.
Biochemical and biophysical research communications
Song Z,Li S,Zhang C,Yuan L,Han L,Liu Y
Tue Oct 01 00:00:00 EDT 2019
Rosiglitazone ameliorates bile duct ligation-induced liver fibrosis by down-regulating NF-κB-TNF-α signaling pathway in a PPARγ-dependent manner.
Biochemical and biophysical research communications
Wei Z,Zhao D,Zhang Y,Chen Y,Zhang S,Li Q,Zeng P,Li X,Zhang W,Duan Y,Han J,Yang X
Tue Nov 19 00:00:00 EST 2019
Geniposide attenuates Aβ25-35-induced neurotoxicity via the TLR4/NF-κB pathway in HT22 cells.
RSC advances
Huang XF,Li JJ,Tao YG,Wang XQ,Zhang RL,Zhang JL,Su ZQ,Huang QH,Deng YH
Tue May 22 00:00:00 EDT 2018
The Nox1/Nox4 inhibitor attenuates acute lung injury induced by ischemia-reperfusion in mice.
PloS one
Cui Y,Wang Y,Li G,Ma W,Zhou XS,Wang J,Liu B
Mon May 27 00:00:00 EDT 2019
Diosmetin Attenuates Akt Signaling Pathway by Modulating Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB)/Inducible Nitric Oxide Synthase (iNOS) in Streptozotocin (STZ)-Induced Diabetic Nephropathy Mice.
Medical science monitor : international medical journal of experimental and clinical research
Jiang Y,Liu J,Zhou Z,Liu K,Liu C
Tue Oct 02 00:00:00 EDT 2018
IL-1β promotes the migration of olfactory epithelium neural stem cells through activating matrix metalloproteinase expressions.
Pathology, research and practice
Pu Y,Liu H,Xu H,Liu H,Cheng Y,Chen X,Xu W,Xu Y,Fan J
Wed Aug 01 00:00:00 EDT 2018
