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This gene encodes a zinc finger protein transcriptional repressor. The encoded protein is part of the methyl-CpG-binding protein-1 complex, which represses gene expression by deacetylating methylated nucleosomes. Mutations in this gene are linked to intellectual disability and dysmorphic features associated with cognitive disability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GATA zinc finger domain-containing protein 2B; p66/p68; transcription repressor p66 beta component of the MeCP1 complex; transcription repressor p66 component of the MeCP1 complex; Transcriptional repressor p66-beta
Gene Aliases: AL118180; C430014D17Rik; GATAD2B; KIAA1150; mKIAA1150; MRD18; P66beta; p68
UniProt ID: (Human) Q8WXI9, (Mouse) Q8VHR5
Entrez Gene ID: (Human) 57459, (Mouse) 229542
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