Labtainer Pro BPC products use the same reliable films as existing Thermo Scientific BPCs, providing consistent contact material throughout your workflow. Thermo Scientific Aegis™5-14 and CX5-14 films are both 5-layer, 14 mil cast films produced in a clean room facility. The outer layer is a polyester elastomer coextruded with an ethylene vinyl alcohol (EVOH) barrier layer and a low-density polyethylene (PE) product contact layer. The films are manufactured using no animal-derived components.

The Labtainer Pro BPC is manually inspected after manufacturing - this entails a thorough visual inspection before being packaged and shipped. A 100% helium integrity test is also conducted on the finished BPCs, helping to ensure our best product is delivered to the customer. Labtainer Automated Manufacturing (LAM) technology provides additional production efficiency to an already world-class process.

The Labtainer Pro BPC is designed to be configured with two, three, or four port configurations, without the need for excess ports being placed in the chamber - resulting in fewer potential failure points and no liquid holdup. Porting configurations are available in 1/8, 1/4, 3/8 and 1/2 in. (3.2, 6.4, 9.5, and 12.7 mm) sizes, in any order, without step-up or step-down sizing. The new customizable configuration results in better flow rates, a less tortuous fluid path, and fewer connections.

The manufacturing process for the Labtainer Pro BPC incorporates impulse heat sealing for ports utilizing Labtainer Automated Manufacturing (LAM) technology. This fully automated method of sealing enables a higher level of control over the amount of heat applied, resulting in a consistent and strong seal throughout the finished product.

The protective polyethylene bags used to package the Labtainer Pro BPC are manufactured in a controlled environment, resulting in cleaner packaging with less risk of contaminants and particulate accumulation. The outer bags are prepared with scored notches on the top of either side, with the text, "TEAR OPEN using notch at either side" printed along the seam for an easy, directional-tear opening.

The outer packaging of the Labtainer Pro BPC has been developed to prevent damage due to unpacking with sharps or other tools. The updated packaging features easy-peel tape on the box and an easy-open polyethylene outer bag. The two outer poly bags have been designed to allow for a directional-tear removal, maintaining product integrity and providing a particulate barrier prior to product removal. The packaging tape is an easy-peel tape that can be removed without the assistance of any tools. The outer box has been designed to allow it to open on the shorter side, reducing material and waste.

In our endeavor to attain the highest level of quality assurance in the industry, we implemented
lot-based bacterial endotoxin testing and particulate analysis testing of Labtainer Pro BPC products. The BET test is an in vitro assay for detection and quantitation of bacterial endotoxins to the USP 85 standard. Particulate analysis testing includes procedures for removing, counting, and sizing particulate contaminants on or in the BPC to the USP 788 standard.

All Labtainer Pro BPCs are manufactured using Labtainer Automated Manufacturing (LAM) technology. This automated BPC manufacturing system provides a heightened level of product quality and consistency, and also decreases the likelihood of manufacturing errors. The LAM has been designed to manufacture BPCs in a completely closed manufacturing chamber with HEPA filtration to provide positive oxygen flow.

The handle featured on the Labtainer Pro BPC has been improved for easier operator handling with the addition of a lower handle on the 5, 10, and 20 L units - allowing for more ergonomic manipulation. The shape of the BPC chamber has also been redesigned to allow for better drainage with less manipulation required.

The Labtainer Pro BPC has been engineered with multiple product accessories to maximize productivity and to improve the operator's overall experience working with the product.

• The Labtainer Pro tote provides BPC protection and access to lines without the need to open the lid. The tray inside the tote is designed with a tilt plate to allow for optimal drainage. This product is constructed of medical-grade, high-density polyethylene.
• The Thermo Scientific™ versaCART™ mobile accessory cart is also available as a complementary product to the Labtainer Pro, enabling storage and usage of multiple BPC manifold configurations - while BPCs and tubing are safely stored on the adjustable stainless steel shelves.

The Labtainer Pro BPC provides optimal drainage through ports that do not overly extend into the chamber. The Labtainer Pro BPC also features chamber geometry that tapers to the ports, reducing the holdup volume at the bottom of the BPC. Accessories such as the tote and versaCART unit can also aid in BPC filling and draining.