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In order to effectively study outbreaks and determine disease etiology where pathogens are similar, analytically sensitive panels are needed to support laboratory research studies. Applied Biosystems TrueMark Respiratory Research Panels are analytically sensitive, real-time PCR syndromic panels for the analysis of a wide range of respiratory pathogens including viruses. bacteria, and fungi. Our solutions accurately detect many pathogenic organism targets, thereby helping enable your lab to deliver more informative results while achieving greater efficiency. These solutions also solve many of the challenges associated with the use of immunoassays, culture-based, and even other molecular methods available in research assays today.
Broad pathogen detection—Our solutions detect a broad range of viral, bacterial, and fungal targets in one panel.
Flexible input types—Multiple sample input types can be used, including nasopharyngeal (NP) swabs, bronchoalveolar lavage (BAL), and nasal aspirate
Highly accurate—Enable maximum strain coverage while minimizing off-target cross-reactivity
Scalable and efficient—Our variety of real-time PCR assay formats enable you to process tens to hundreds of samples per day on a single instrument
For Research Use Only. Not for use in diagnostic procedures.
Real-time PCR can detect slow-growing or difficult-to-culture microorganisms and can be used when traditional methods lead to ambiguous results. Our TrueMark Respiratory Research Panel solutions are available in OpenArray Plates, TaqMan Array Cards, and TaqMan Array Plates, and can be used with multiple sample input types, such as nasopharyngeal (NP) swabs, bronchoalveolar lavage (BAL), and nasal aspirate.
Utilizing TaqMan Assays enable rapid, accurate detection and categorization of multiple microorganisms involved in respiratory tract microbiome composition and dynamics. Each TaqMan Array Card can detect up to 41 pathogens, while the OpenArray (OA) Plates can detect up to 33 pathogens with the ability to run up to 24 samples per plate. Both formats are available in two different versions—with or without SARS-CoV 1 & 2 targets—depending on your research needs.
43 |
| Fungus
|
*Only available on TaqMan™ Array Respiratory Tract Microbiota Comprehensive Card
**Only available on TrueMark™ Respiratory Panel 2.0, TaqMan™ Array card
For Research Use Only. Not for use in diagnostic procedures.
Pathogen Type | TaqMan Card | TaqMan Card 2.0 |
Bacterial | S. aureus | S. aureus |
K. pneumoniae | K. pneumoniae | |
C. pneumoniae | C. pneumoniae | |
L. pneumophila | L. pneumophila | |
C. burnetii |
| |
S. pneumoniae | S. pneumoniae | |
M. pneumoniae | M. pneumoniae | |
B. holmesii |
| |
M. catarrhalis | M. catarrhalis | |
B. pertussis | B. pertussis | |
Bordetella | Bordetella | |
H. influenzae | H. influenzae | |
B.atrophaeus | B. atrophaeus | |
Fungal | P. jirovecii | P. jirovecii |
Viral | HHV6 | HHV6 |
EV_pan | EV_pan | |
SARS_CoV | SARS_CoV | |
hPIV1 | hPIV1 | |
HHV5 | HHV5 | |
MERS_CoV | MERS_CoV | |
CoV_OC43 | CoV_OC43 | |
HHV3 | HHV3 | |
Mumps | Mumps | |
EV_D68 | EV_D68 | |
hPIV3 | hPIV3 | |
CoV_229E | CoV_229E | |
hPIV2 | hPIV2 | |
CoV_NL63 | CoV_NL63 | |
CoV_HKU1 | CoV_HKU1 | |
HHV4 | HHV4 | |
AdV_1of2 | AdV_1of2 | |
AdV_2of2 | AdV_2of2 | |
HBoV | HBoV | |
hMPV | hMPV | |
hPIV4 | hPIV4 | |
HPeV | HPeV | |
Flu_A_H1 | Flu_A_H1 | |
Flu_A_H3 | Flu_A_H3 | |
Flu_A_pan | Flu_A_pan | |
Flu_B_pan | Flu_B_pan | |
Measles | Measles | |
RSVA | RSVA | |
RSVB | RSVB | |
RV_1of2 | RV_1of2 | |
RV_2of2 | RV_2of2 | |
| SARS-CoV2S | |
| SARS-CoV2N | |
Control | Xeno | Xeno |
RPPH1 | RPPH1 | |
18s | 18s |
Pathogen Type | OpenArray Plate | OpenArray Plate 2.0 |
Bacterial | S. aureus | S. aureus |
K. pneumoniae | K. pneumoniae | |
C. pneumoniae | C. pneumoniae | |
L. pneumophila | L. pneumophila | |
S. pneumoniae | S. pneumoniae | |
M. pneumoniae | M. pneumoniae | |
B. pertussis | B. pertussis | |
Bordetella | Bordetella | |
H. influenzae | H. influenzae | |
Viral | HHV6 | HHV6 |
EV_pan | EV_pan | |
hPIV1 | hPIV1 | |
HHV5 | HHV5 | |
CoV_OC43 | CoV_OC43 | |
HHV3 |
| |
EV_D68 | EV_D68 | |
hPIV3 | hPIV3 | |
CoV_229E | CoV_229E | |
hPIV2 | hPIV2 | |
CoV_NL63 | CoV_NL63 | |
CoV_HKU1 | CoV_HKU1 | |
HHV4 | HHV4 | |
AdV_1of2 | AdV_1of2 | |
AdV_2of2 | AdV_2of2 | |
HBoV |
| |
hMPV | hMPV | |
hPIV4 | hPIV4 | |
Flu_A_H1 | Flu_A_H1 | |
Flu_A_H3 | Flu_A_H3 | |
Flu_A_pan | Flu_A_pan | |
Flu_B_pan | Flu_B_pan | |
RSVA | RSVA | |
RSVB | RSVB | |
RV_1of2 | RV_1of2 | |
RV_2of2 | RV_2of2 | |
| SARS-CoV2S | |
| SARS-CoV2N | |
Control | IC Xeno | IC Xeno |
IC B.atrophaeus | IC B.atrophaeus | |
IC RNase P | IC RNase P |
To download a PDF version of the information above, please visit Pathogen Target Guide for Respiratory Panels.
For Research Use Only. Not for use in diagnostic procedures.
TaqMan Assays for respiratory pathogens have undergone rigorous bioinformatic analysis to help ensure maximum strain coverage while minimizing off-target cross-reactivity. Each assay has been tested with target and non-target genomic RNA or DNA isolated from target organisms (nucleic acid acquired from ATCC) in our inclusivity panel.
Pathogen | True positive* | False negative** | Concordance |
Adenovirus | 20 | 1 | 95.24% |
Coronavirus 229E | 2 | 0 | 100.00% |
Coronavirus HKU1 | 1 | 0 | 100.00% |
Coronavirus OC34 | 1 | 0 | 100.00% |
Influenza A | 4 | 0 | 100.00% |
Influenza A/H1 | 6 | 0 | 100.00% |
Influenza A/H3 | 16 | 0 | 100.00% |
Influenza B | 16 | 0 | 100.00% |
hMPV | 16 | 0 | 94.12% |
hPIV1 | 10 | 1 | 90.91% |
hPIV2 | 10 | 0 | 100.00% |
hPIV3 | 12 | 0 | 100.00% |
RSV | 6 | 0 | 100.00% |
RSVA | 17 | 1 | 94.44% |
RSVB | 16 | 1 | 100.00% |
Rhinovirus, enterovirus | 27 | 0 | 100.00% |
Total | 180 | 5 | 97.30% |
* Call from the vendor ** Call not detected when tested on TaqMan Array Card Assay (TAC) The analytical testing characteristics of the assays on the TaqMan Array Respiratory Tract Microbiota Comprehensive Card were examined by testing with 180 procured samples. The control samples included in this study have application in respiratory disease research and cover 16 key respiratory viruses. |
The QuantStudio family of instruments can meet any throughput requirement. For higher throughput laboratories, leverage our OpenArray nanofluidic technology. A complete end-to-end solution is available and includes the Thermo Scientific KingFisher Flex benchtop automated DNA/RNA extraction instrument, convenient extraction and purification kits, and the OpenArray AccuFill System. Combined, these systems can automate sample prep and liquid handling to enable the processing of hundreds to thousands of samples per day.
Whether you already own an instrument or are considering an expansion to your capabilities, your sample processing and throughput requirements can be addressed through different formats compatible with your instrument (i.e. TaqMan Array Cards, 96- or 384-well plates, or single tube assays) with made-to-stock or custom panels.
Explore QuantStudio PCR Systems, a flexible and scalable real-time PCR platform.
Order the TaqMan™ Array Respiratory Tract Microbiota Comprehensive Card or TrueMark™ Respiratory Panel 2.0, TaqMan™ Array Card
For Research Use Only. Not for use in diagnostic procedures.
When adopting a new testing method for your research needs, we can assist in enabling the verification of the workflow to help ensure a successful launch. Our analytical validation (AV) consulting services can speed up the launch process by up to 75% and cut costs by up to half. Our expert team will consult to help develop and optimize your research workflow, while providing data analysis support and template documentation to fully maximize your instrument and reagent investment.
Consulting services offered for enabling the analytical validation cannot be used to validate a clinical diagnostic workflow and can only be used to support ongoing true research efforts.
For Research Use Only. Not for use in diagnostic procedures.