DXR3 Raman Microscope

DXR3 Raman Microscope overview

Other capabilities include:

• Pre-aligned and lock-in-place components that use automatic recognition and stored alignment, allowing any user to reconfigure an instrument in seconds
• Lasers and other components that can be interchanged and shared with every instrument in the DXR3 Raman family
• Optional, automated polarized Raman capabilities that provide structural information that complements chemical information
• The ability to add new wavelengths without tools or a service engineer visit
  

The DXR3 Raman Microscope is independently certified as class-1 laser safe. (Note: Optional fiber-optic accessory and some other optional accessories are Class IIIb laser devices requiring laser safety precautions and laser safety eyewear.) The laser is physically blocked from the visual viewing path to prevent exposure to the eyes while viewing.

A complete package for DQ/IQ/OQ/PQ validation is available including extensive documentation and automated software protocols. In addition, Omnic D/S software offers 21 CFR Part 11 compliance.

The DXR3 Raman Microscope offers spatial resolution as fine as 540 nm resolution and confocal depth resolution as fine as 1.7 μm on an ideal sample. The full spectral range of 3500-50 cm^-1 can be captured with a single exposure of the CCD to avoid stitching artifacts. An extended spectral range to 6,000 cm^-1 is available for 532 nm laser.

The DXR3 supports multiple excitation lasers: 455 nm, 532 nm high brightness, 532 nm high power, 633 nm high brightness, 633 nm high power, 785 nm high brightness, and 785 nm high power. Automatic fluorescence correction available with all excitation lasers.

The microscope also provides research-quality Olympus viewing optics. Moreover, automatic intensity correction generates spectra that are comparable between instruments and different excitation lasers, and multi-dimensional wavelength calibration provides accurate wavelength calibration across the entire spectral range.

The DXR3 Raman Microscope’s proprietary triplet spectrograph provides exceptional peak shape and maintains focus at all wavelengths. Users can take advantage of software-controlled switching between confocal and high-energy collection modes. And a proprietary algorithm for automated cosmic ray rejection and high-quality laser line filters ensures artifact-free spectra.

Other performance features include:

• Lasers depolarized to avoid confusing sample orientation effects
• A Laser Power Regulator that provides active monitoring of laser power and ensures reproducible laser excitation power over the lifetime of lasers and even after replacing lasers
• Optimized gratings for each excitation laser to avoid performance sacrifices of systems that share gratings for multiple excitation lasers
• Proprietary auto alignment that ensures the system can be maintained in like-new condition
• Proprietary Smart-backgrounds that automatically remove CCD dark energy profile