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Spatial biology is dedicated to understanding the location of biomarkers and cell types within tissues and organs. Spatial omics is the combined studies of spatial transcriptomics and spatial proteomics, and used to understand both RNA and protein organization or expression within a tissue. Our resource center is developed by scientists to help start or evolve IHC experiments into multi-biomarker experiments. Get started with our educational videos, protocols, tips and tricks to enable your multiplex imaging experiment.
Learn from our researchers the techniques and reagents to transform your imaging experiments into spatial phenotyping. Our researchers demonstrate the techniques and reagents to transform your imaging experiments into spatial phenotyping. Read and see data about best practices for tissue handling, selection of targets and antibody panels, and colorimetric and fluorescence staining tools from our experts for multiplexing IHC experiments in spatial biology.
Watch our webinars and virtual training sessions to gather tips, tricks, and best practices using Thermo Fisher Scientific products for your spatial biology experiments. Learn about tissue preparation and antibody selection for successful multiplexing immunofluorescence and analyzing single-cell data for spatial phenotyping.
Learn from the leaders of the Omics and imaging field covering key experimental and computational advances.
Spatial biology provides the location of biomarkers and cell types within tissues and organs to enable the assessment of cellular communication and correlated structural organization. Analyze single cells in spatial context with our imaging analysis products. Thermo Fisher Scientific offers high-quality reagents, assays, and instruments for single-cell analysis.
These imaging protocols detail what you need to help support a successful multiplex IHC or spatial biology experiment, including tips, detailed steps, and lists of needed supplies. Learn how to use antibodies, common IHC supplies, labels, mountants, and counterstains to achieve stunning cellular images.
Read our articles about experimental techniques and best practices for obtaining clear single-cell data from tissue used in immunohistochemistry experiments for spatial biology.
Find helpful tools below to help you plan your spatial imaging experiments. Use the interactive SpectraViewer tool to view excitation and emission spectra and select the optimal fluorescent dyes for multiplexing in your experiment for use with various fluorescence instruments. Using our free Stain-iT web software, simulate cell staining with antibodies or dyes to gain insights for experiment planning and spectral analysis.
Photo credit, headline image: IBEX image of B cells in the germinal center and medulla of the human lymph node. Image is courtesy of Drs. Andrea J. Radtke and Ronald N. Germain.
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