Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
With preparative columns, one size does not fit all. Whether you need unique chemistries for difficult separations to purify your compound of interest, robust columns for longer use, or budget-friendly solutions for routine applications, our preparative HPLC column portfolio has something to meet your needs. Our full range of customizable column hardware with optional XtendedLife technology offers robust, reproducible performance and expanded column capabilities in a wide variety of stationary phase chemistries, making it easy to scale up from your current analytical method.
Thermo Scientific preparative HPLC columns are available in 40+ stationary phase chemistries, allowing for maximum flexibility and ensuring that you have options to scale up your analytical workflows with chemistry continuity for easy method transfer.
Our preparative stationary phases are offered in three families:
Popular Thermo Scientific phases | We have expanded our current offering of popular Thermo Scientific column chemistries, allowing customers to seamlessly scale up their current analytical methods. Meet the most challenging separations with chemistries that are manufactured to the highest standards and provide excellent selectivity and separation for a variety of applications. Available column chemistries include Hypersil GOLD, Accucore, MAbPac, and DNAPac. |
Hypersil PREP phases | An excellent choices for routine applications that require development from analytical to preparative HPLC scale. Available in C18, C8, silica, ODS, BDS, and phenyl phases, the Hypersil PREP range has been designed to provide good selectivity for a wide range of applications. |
Hypersil PREP HS phases | Our PREP HS line features high surface area particles with a 100 Å pore size to maximize sample retention and loading. An excellent choice for small molecule and drug purification applications, Hypersil PREP HS is available in C18, C8, silicone, and phenyl phases. |
If there is a Thermo Scientific stationary phase you are currently using and would like to obtain in preparative scale or would like to discuss a specific phase that is not listed above, we would be happy to discuss your requirements. Please contact your local sales representative for customer specific orders. Please note that custom built columns are not eligible for returns.
Pore size (Å) | Surface area (m2/g) | Carbon load (%) | USP code | pH range | |
---|---|---|---|---|---|
Hypersil GOLD C18 | 175 | 220 | 10 | L1 | 2 to 9 |
Hypersil GOLD C8 | 175 | 220 | 8 | L7 | 2 to 9 |
Hypersil GOLD aQ | 175 | 220 | 12 | L1 | 2 to 9 |
Hypersil GOLD C4 | 175 | 220 | 5 | L26 | 2 to 8 |
Hypersil GOLD Phenyl | 175 | 220 | 8 | L11 | 2 to 8 |
Hypercarb | 250 | 120 | 100 | L109 | 0 to 14 |
Syncronis C18 | 100 | 320 | 16 | L1 | 2 to 9 |
Syncronis HILIC | 100 | 320 | 5 | None | 2 to 8 |
Accucore XL C18 | 80 | 90 | 7 | L1 | 1 to 11 |
Accucore XL C8 | 80 | 90 | 4 | L7 | 2 to 9 |
DNAPac RP | Proprietary wide pore | 22-24 | N/A | None | 0 to 14 |
DNAPac PA200 | Nonporous | N/A | N/A | None | 4 to 10 |
MAbPac | Nonporous | N/A | N/A | None | 2 to 12 |
ProPac | Nonporous | N/A | N/A | None | 2 to 12 |
Pore size (Å) | Surface area (m2/g) | Carbon load (%) | USP code | pH range | |
---|---|---|---|---|---|
Hypersil PREP C18 BDS | 145 | 185 | 11 | L1 | 2 to 8 |
Hypersil PREP C8 BDS | 145 | 185 | 7 | L7 | 2 to 8 |
Hypersil PREP ODS | 130 | 195 | 10 | L1 | 2 to 8 |
Hypersil PREP Si BDS | 145 | 185 | 0 | L3 | 2 to 7 |
Hypersil PREP Si | 130 | 195 | 0 | L3 | 2 to 7 |
Hypersil PREP Phenyl BDS | 145 | 185 | 5 | L11 | 2 to 8 |
Pore size (Å) | Surface area (m2/g) | Carbon load (%) | USP code | pH range | |
---|---|---|---|---|---|
Hypersil PREP C18 HS | 100 | 350 | 15 | L1 | 2 to 9 |
Hypersil PREP C8 HS | 100 | 350 | 7 | L7 | 2 to 8 |
Hypersil PREP Si HS | 100 | 350 | 0 | L3 | 2 to 7 |
Hypersil PREP Phenyl HS | 100 | 350 | 9 | L11 | 2 to 8 |
We offer three column hardware options based on column inner diameter (I.D.) and column performance needs:
Use this online tool to determine best starting conditions for scaling methods between analytical to preparative HPLC conditions. The tool will calculate the new injection volume, flow rate, gradient table and expected eluent usage. Just insert your current method conditions and your new column dimensions to get up and running faster.
Your complete, interactive, digital guide to all Thermo Scientific chromatography columns and consumables products. Our enhanced online 2022/2023 catalog features easy access to product information, key application notes, and brand-new selector tools.
Learn how Preparative HPLC columns help easily scale up a methods already developed on a small analytical column to a larger preparative HPLC column.
* Required field