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Feline IL-5 quantitates feline IL-5 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant feline IL-5.
IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : IL5
Gene ID : (Cat) 493803
Gene symbol : IL5
Protein Aliases : Eosinophil differentiation factor, IL-5, Interleukin-5, T-cell replacing factor, TRF
UniProt ID (Cat) O77515
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