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Human CD155/PVR quantitates human CD155/PVR in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CD155/PVR.
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : CD155, HVED, Necl-5, NECL5, PVR, PVS, TAGE4
Gene ID : (Human) 5817
Gene symbol : PVR
Protein Aliases : CD155, NECL-5, Nectin-like protein 5, Poliovirus receptor
UniProt ID (Human) P15151
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