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Human CRTAC1 quantitates human CRTAC1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CRTAC1.
CRTAC1 encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : ASPIC, ASPIC1, CEP-68, CEP68, CRTAC1
Gene ID : (Human) 55118
Gene symbol : CRTAC1
Protein Aliases : 68 kDa chondrocyte-expressed protein, acidic secreted protein in cartilage, ASPIC, Cartilage acidic protein 1, CEP-68, chondrocyte expressed protein 68 kDa CEP-68
UniProt ID (Human) Q9NQ79
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