Technical guide & protocol Tech Support

Product Specifications

Analytical sensitivity

0.6 ng/mL

Assay range

0.6-150 ng/mL

Sample type/volume

Plasma
50 µL
Serum
50 µL
Supernatant
50 µL

Hands-on time

1 hr 20 min

Time-to-result

4 hr 45 min

Homogenous (no wash)

No

Interassay CV

<12%

Intraassay CV

<10%

Instrument

Colorimetric Microplate Reader

Product size

96 Tests

Contents

Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers

Shipping conditions

Wet ice

Storage

2-8°C

Protein name

CXCL17

Species (tested)

Human

Assay kit format

Sandwich ELISA Kit

Detector antibody conjugate

Biotin

Label or dye

HRP

About This Kit

Human CXCL-17 quantitates human CXCL-17 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CXCL-17.

Target information

CXCL17 is a chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. In particular, CXCL17 is a mucosal chemokine that attracts dendritic cells and blood monocytes to the lungs. CXCL17 plays a role in angiogenesis and possibly in the development of tumors. Further, CXCL17 acts as an anti-inflammatory in the stomach and may play a role in the innate defense against infections. CXCL17 also activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. 4-Cys CXCL17 seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17. Diseases associated with CXCL17 dysfunction include cholera.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Gene aliases : CXCL17, Dcip1, DMC, UNQ473, UNQ473/PRO842, VCC-1, VCC1

Gene ID : (Human) 284340

Gene symbol : CXCL17

Protein Aliases : 6-Cys CXCL17, C-X-C motif chemokine 17, chemokine (C-X-C motif) ligand 17, Dendritic cell and monocyte chemokine-like protein, DMC, VEGF co-regulated chemokine 1, VEGF coregulated chemokine 1

UniProt ID (Human) Q6UXB2

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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