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Human Cadherin 13 quantitates human Cadherin 13 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Cadherin 13.
The protein encoded by this gene has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : CDH13, CDHH, P105
Gene ID : (Human) 1012
Gene symbol : CDH13
Protein Aliases : cadherin 13, H-cadherin (heart), Cadherin-13, H-cadherin, Heart cadherin, P105, T-cad, T-cadherin, Truncated cadherin
UniProt ID (Human) P55290
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