Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Human CytokeRatin 8/KRT8 quantitates human Cytokeratin 8/KRT8 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Cytokeratin 8/KRT8.
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : CARD2, CK-8, CK8, CYK8, K2C8, K8, KO, KRT8
Gene ID : (Human) 3856
Gene symbol : KRT8
Protein Aliases : CK-8, Cytokeratin-8, K8, keratin 8, type II, Keratin, type II cytoskeletal 8, Keratin-8, Type-II keratin Kb8
UniProt ID (Human) P05787
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