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Human ESAM quantitates human ESAM in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human ESAM.
ESAM is a 55-kDa membrane protein composed of 2 extracellular Ig domains, a single transmembrane domain, and a 120 amino acid cytoplasmic domain. ESAM is related to members of the junctional adhesion molecule (JAM) family, and is expressed on endothelial cells and activated platelets. ESAM at endothelial tight junctions plays a role in the regulation of vascular permeability, in response to agents such as VEGF or extravasating neutrophils.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : ESAM, UNQ220/PRO246, W117m
Gene ID : (Human) 90952
Gene symbol : ESAM
Protein Aliases : 2310008D05Rik, Endothelial cell-selective adhesion molecule, HUEL (C4orf1)-interacting protein, LP4791 protein
UniProt ID (Human) Q96AP7
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