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Human Eotaxin 3 quantitates human Eotaxin 3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Eotaxin 3.
Eotaxin-3 is a small cytokine belonging to the CC chemokine family that is also called CCL26, Chemokine (C-C motif) ligand 26. Chemokines play pivotal roles in health and disease by controlling migration and tissue localization of specific types of cells expressing their cognate receptors. Eotaxin-3 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3. It is expressed by several tissues including heart, lung and ovary, and in endothelial cells that have been stimulated with the cytokine interleukin 4. This gene for chemokine is located on human chromosome 7. Eotaxin-3 induced migration of eosinophils and basophils only at a 10-fold higher concentration than eotaxin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : CCL26, IMAC, MIP-4a, MIP-4alpha, SCYA26, TSC-1, UNQ216/PRO242
Gene ID : (Human) 10344
Gene symbol : CCL26
Protein Aliases : C-C motif chemokine 26, CC chemokine IMAC, chemokine (C-C motif) ligand 26, chemokine N1, Eotaxin-3, Macrophage inflammatory protein 4-alpha, MIP-4-alpha, small inducible cytokine A26, small inducible cytokine subfamily A (Cys-Cys), member 26, Small-inducible cytokine A26, Thymic stroma chemokine-1, TSC-1
UniProt ID (Human) Q9Y258
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