Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
The Human Fibroblast Growth Factor 6 (Hu FGF6) ELISA quantitates Hu FGF6 in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu FGF6.
Principle of the method
The Human FGF6 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
Rigorous validation
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
FGF-6 is a secreted, heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-6 is expressed in leukemia cell lines with platelet megakaryocytic differentiation potential. It signals through FGFR 1c, 2c, and 4.4
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : FGF6, HBGF-6, HST2, HSTF2
Gene ID : (Human) 2251
Gene symbol : FGF6
Protein Aliases : FGF-6, Fibroblast growth factor 6, HBGF-6, Heparin secretory-transforming protein 2, Heparin-binding growth factor 6, HST-2, HSTF-2
UniProt ID (Human) P10767
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