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Human FOLR2 quantitates human FOLR2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human FOLR2.
FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : BETA-HFR, FBP, FBP/PL-1, FOLR2, FR-BETA, FR-P3
Gene ID : (Human) 2350
Gene symbol : FOLR2
Protein Aliases : FBP, Folate receptor 2, folate receptor 2 (fetal), Folate receptor beta, folate receptor, beta, Folate receptor, fetal/placental, folate-binding protein, FR-beta, Placental folate-binding protein
UniProt ID (Human) P14207
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