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Product Specifications

Analytical sensitivity

12.5 pg/mL

Assay range

12.5-3,000 pg/mL

Sample type/volume

Supernatant
50 µL
Plasma
50 µL
Serum
50 µL

Hands-on time

1 hr 20 min

Time-to-result

4 hr 45 min

Homogenous (no wash)

No

Interassay CV

<12%

Intraassay CV

<10%

Instrument

Colorimetric Microplate Reader

Product size

96 Tests

Contents

Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers

Shipping conditions

Wet ice

Storage

2-8°C

Protein name

Granzyme H

Species (tested)

Human

Assay kit format

Sandwich ELISA Kit

Detector antibody conjugate

Biotin

Label or dye

HRP

About This Kit

Human Granzyme H quantitates human Granzyme H in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Granzyme H.

Target information

This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Gene aliases : CCP-X, CGL-2, CGL2, CSP-C, CTLA1, CTSGL2, GZMH

Gene ID : (Human) 2999

Gene symbol : GZMH

Protein Aliases : Cathepsin G-like 2, cathepsin G-like 2, protein h-CCPX, CCP-X, CSP-C, CTSGL2, Cytotoxic serine protease C, Cytotoxic T-lymphocyte proteinase, cytotoxic T-lymphocyte-associated serine esterase 1, cytotoxin serine protease-C, Granzyme H, granzyme H (cathepsin G-like 2, protein h-CCPX)

UniProt ID (Human) P20718

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