Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Human HPRG quantitates human HPRG in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human HPRG.
HRG contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : HPRG, HRG, HRGP, THPH11
Gene ID : (Human) 3273
Gene symbol : HRG
Protein Aliases : Histidine-proline-rich glycoprotein, Histidine-rich glycoprotein, HPRG
UniProt ID (Human) P04196
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