Technical guide & protocol Tech Support

Product Specifications

Analytical sensitivity

0.05 ng/mL

Assay range

0.05-12ng/mL

Sample type/volume

Supernatant
50 µL
Plasma
50 µL
Serum
50 µL

Hands-on time

1 hr 20 min

Time-to-result

4 hr 45 min

Homogenous (no wash)

No

Interassay CV

<12%

Intraassay CV

<10%

Instrument

Colorimetric Microplate Reader

Product size

96 Tests

Contents

Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers

Shipping conditions

Wet ice

Storage

2-8°C

Protein name

IL17RC

Species (tested)

Human

Assay kit format

Sandwich ELISA Kit

Detector antibody conjugate

Biotin

Label or dye

HRP

About This Kit

Human IL-17RC quantitates human IL-17RC in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IL-17RC.

Target information

This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Gene aliases : CANDF9, IL17-RL, IL17RC, IL17RL, UNQ6118/PRO20040/PRO38901

Gene ID : (Human) 84818

Gene symbol : IL17RC

Protein Aliases : IL-17 receptor C, IL-17RL, IL17F receptor, IL17Rhom, Interleukin-17 receptor C, Interleukin-17 receptor homolog, Interleukin-17 receptor-like protein, ZcytoR14

UniProt ID (Human) Q8NAC3

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