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Human IL-24 quantitates human IL-24 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IL-24.
Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : C49A, FISP, IL10B, IL24, MDA7, MOB5, ST16
Gene ID : (Human) 11009
Gene symbol : IL24
Protein Aliases : IL-24, IL-4-induced secreted protein, Interleukin-24, MDA-7, melanocyte-associated Mda-7, Melanoma differentiation-associated gene 7 protein, suppression of tumorigenicity 16 (melanoma differentiation), Suppression of tumorigenicity 16 protein
UniProt ID (Human) Q13007
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