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Human KIRREL3 quantitates human KIRREL3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human KIRREL3.
The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. The protein encoded by this gene is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : KIAA1867, KIRRE, KIRREL3, MRD4, NEPH2, PRO4502, UNQ5923/PRO4502/PRO19814
Gene ID : (Human) 84623
Gene symbol : KIRREL3
Protein Aliases : Kin of IRRE-like protein 3, Kin of irregular chiasm-like protein 3, nephrin-like 2, Nephrin-like protein 2
UniProt ID (Human) Q8IZU9
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