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Human Kininogen quantitates human Kininogen in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Kininogen.
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : BDK, BK, KNG, KNG1
Gene ID : (Human) 3827
Gene symbol : KNG1
Protein Aliases : Alpha-2-thiol proteinase inhibitor, bradykinin, Fitzgerald factor, High molecular weight kininogen, HMWK, Kininogen-1, Williams-Fitzgerald-Flaujeac factor
UniProt ID (Human) P01042
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