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Human LBP quantitates human LBP in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human LBP.
The LBP protein is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Finally, this gene is found on chromosome 20, immediately downstream of the BPI gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : BPIFD2, LBP
Gene ID : (Human) 3929
Gene symbol : LBP
Protein Aliases : BPI fold containing family D, member 2, LBP, Lipopolysaccharide-binding protein, LPS-binding protein
UniProt ID (Human) P18428
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