Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
The Human Nerve Growth Factor Receptor (Hu NGFR) ELISA quantitates Hu NGFR in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu NGFR.
Principle of the method
The Human NGFR solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
Rigorous validation
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo. Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, to enhance our understanding of a wide range of phenomena in the development, plasticity and repair of the nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : CD271, Gp80-LNGFR, NGFR, p75(NTR), p75NTR, TNFRSF16
Gene ID : (Human) 4804
Gene symbol : NGFR
Protein Aliases : CD271, Gp80-LNGFR, low affinity nerve growth factor receptor, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, Low-affinity nerve growth factor receptor p75NGFR, Low-affinity nerve growth factor receptor p75NGR, NGF receptor, p75 ICD, TNFR superfamily, member 16, Tumor necrosis factor receptor superfamily member 16
UniProt ID (Human) P08138
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