Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Human SGK1 quantitates human SGK1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human SGK1.
SGK (SGK1) is a serine/threonine kinase that may be a transcriptional target for p38/MAPK in hepatoma cells. SGK plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : SGK, SGK1
Gene ID : (Human) 6446
Gene symbol : SGK1
Protein Aliases : serine/threonine protein kinase SGK, Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1, Sgk1 variant i3
UniProt ID (Human) O00141
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