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Human SOD3 quantitates human SOD3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human SOD3.
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : EC-SOD, SOD3
Gene ID : (Human) 6649
Gene symbol : SOD3
Protein Aliases : EC-SOD, Extracellular superoxide dismutase [Cu-Zn], testicular tissue protein Li 175
UniProt ID (Human) P08294
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