Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
900-K44K consists of: 900-K44 (capture antibody, detection antibody, and protein standard), and AVIDIN-60UL (avidin HRP-conjugate).
Human Thrombopoietin ABTS ELISA Development Kit contains the key components required for the quantitative measurement of natural and/or recombinant human Thrombopoietin in a sandwich ELISA format. Human Thrombopoietin ABTS ELISA Development Kit contains enough material to assay the target cytokine in at least 1,000 ELISA plate wells.
The ABTS ELISA Buffer Kit (Product # 900-K00), sold separately, is recommended to be used in conjunction with this ABTS ELISA Development Kit for optimal performance. This buffer kit contains all the necessary components to assay ten 96-well ELISA plates (included) and contains detailed handling instructions.
Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, ultimately, to the production of platelets (thrombopoiesis). Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : MGDF, MKCSF, ML, MPLLG, THCYT1, THPO, TPO
Gene ID : (Human) 7066
Gene symbol : THPO
Protein Aliases : C-mpl ligand, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, megakaryocyte stimulating factor, MGDF, ML, MPL ligand, Myeloproliferative leukemia virus oncogene ligand, prepro-thrombopoietin, Thrombopoietin
UniProt ID (Human) P40225
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