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Human cIAP-1/BIRC2/hIAP-2 quantitates human cIAP-1/BIRC2/hIAP-2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human cIAP-1/BIRC2/hIAP-2.
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : API1, BIRC2, c-IAP1, cIAP1, Hiap-2, HIAP2, MIHB, RNF48
Gene ID : (Human) 329
Gene symbol : BIRC2
Protein Aliases : apoptosis inhibitor 1, baculoviral IAP repeat-containing 2, Baculoviral IAP repeat-containing protein 2, C-IAP1, Cellular inhibitor of apoptosis 1, hIAP-2, IAP homolog B, IAP-2, Inhibitor of apoptosis protein 2, NFR2-TRAF signalling complex protein, RING finger protein 48, RING-type E3 ubiquitin transferase BIRC2, TNFR2-TRAF-signaling complex protein 2
UniProt ID (Human) Q13490
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