Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Mouse Activin A quantitates mouse Activin A in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse Activin A.
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Activin A mutations are associated with fibrodysplasia ossificans progressive.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : Inhba
Gene ID : (Mouse) 16323
Gene symbol : Inhba
Protein Aliases : Activin beta-A chain, Inhibin beta A chain
UniProt ID (Mouse) Q04998
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