Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
The Mouse Eotaxin-2 (CCL24) ELISA quantitates Ms Eotaxin-2 in mouse serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Ms Eotaxin-2.
Principle of the method
The Mouse Eotaxin-2 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
Rigorous validation
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
Eotaxin 2 belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : Ccl24, CKb-6, MPIF-2, Scya24
Gene ID : (Mouse) 56221
Gene symbol : Ccl24
Protein Aliases : C-C motif chemokine 24, CC chemokine CCL24, Eosinophil chemotactic protein 2, Eotaxin-2, Small-inducible cytokine A24, small inducible cytokine A24
UniProt ID (Mouse) Q9JKC0
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