Technical guide & protocol Tech Support

Product Specifications

Analytical sensitivity

0.8 ng/mL

Assay range

0.8-200 ng/mL

Sample type/volume

Serum
50 µL
Plasma
50 µL
Supernatant
50 µL

Hands-on time

1 hr 20 min

Time-to-result

4 hr 45 min

Homogenous (no wash)

No

Interassay CV

<12%

Intraassay CV

<10%

Instrument

Colorimetric Microplate Reader

Product size

96 Tests

Contents

Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers

Shipping conditions

Wet ice

Storage

2-8°C

Protein name

GREM1

Species (tested)

Mouse

Assay kit format

Sandwich ELISA Kit

Detector antibody conjugate

Biotin

Label or dye

HRP

About This Kit

Mouse Gremlin-1 quantitates mouse Gremlin-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse Gremlin-1.

Target information

In Xenopus, Gremlin belongs to a novel gene family that act as BMP antagonists in embryonic explants. The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13--> q15. DRM-specific mRNA is expressed in different human tissues, including brain, ovary, intestine and colon. It has been suggested that down-regulation of DRM is associated with tumor progression, and support the hypothesis that human DRM may play an important role during both neuroembryological development and carcinogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Gene aliases : Cktsf1b1, Drm, Grem, Grem1, ld

Gene ID : (Mouse) 23892

Gene symbol : Grem1

Protein Aliases : Cysteine knot superfamily 1, BMP antagonist 1, Down-regulated in Mos-transformed cells protein, down-regulated in v-mos-transformed cells, Gremlin-1

UniProt ID (Mouse) O70326

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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