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Search Thermo Fisher Scientific
Mouse Osteoactivin quantitates mouse Osteoactivin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse Osteoactivin.
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : DC-HIL, Dchil, Gpnmb, Hgfin, ipd, Nmb
Gene ID : (Mouse) 93695
Gene symbol : Gpnmb
Protein Aliases : DC-HIL, dendritic cell-associated heparin sulfate proteoglycan-dependent integrin ligand, Dendritic cell-associated transmembrane protein, iris pigment dispersion, Osteoactivin, Transmembrane glycoprotein NMB
UniProt ID (Mouse) Q99P91
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