Duration: 27 minutes
90% of new molecules and roughly 40% of the top solid oral drugs marketed in the U.S. and Europe have generally low solubility. Hot-melt extrusion (HME) can help to overcome these challenges as the technique can enhance the solubility and bioavailability of poorly soluble active pharmaceutical ingredients (APIs). Transition from inefficient batch processing to continuous manufacturing, and produce novel delivery systems such as injectable implants and oral dispersible films (ODFs).
We invite you to watch this on-demand webinar introducing you to hot-melt extrusion for pharmaceutical applications. Our Pharma Applications Specialist, Dr. Margarethe Richter, will cover the following topics:
• Introduction to the hot-melt extrusion process
• Current pharmaceutical challenges addressed by HME
• Advantages of HME over alternative techniques i.e., spray drying
• Dosage forms produced by HME
• Scale-out vs. scale-up with lab-scale extruders
