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Unlock the potential of next-generation antibody therapeutics

Our aim is to help you optimize your downstream process for your next-generation antibody therapeutics. Explore valuable insights into the use of our affinity chromatography resins, which have been specifically developed to address the challenges associated with engineered monoclonal antibodies.

Find your resin using this 3D antibody purification tour


Articles

Overcoming Purification Challenges in Antibody Therapeutics Manufacturing with Subdomain-Specific Affinity Solution

Discover resins—developed to bind antibody subdomain regions—that can support the downstream process for a variety of antibody formats.

Monoclonal Antibody Aggregate Polish and Viral Clearance Using Hydrophobic-Interaction Chromatography

Gain insight into using HIC purification, including viral clearance data, for monoclonal antibodies requiring aggressive strategies for aggregate clearance.

Novel Hydrophobic Interaction Chromatography Resins for Next Generation Biotherapeutic Challenges

Learn how POROS HIC resins provide excellent resolution, capacity, and product recovery for a wide range of biomolecules.

Improving Aggregate Removal to Enhance Clinical Manufacturing of Mabs

Gain knowledge from this case study describing mAb aggregate removal using HIC in flow-through mode, resulting in improved process efficiency and productivity, compared to a mixed-mode bind-elute step.

Overcoming Purification Challenges in Antibody Therapeutics Manufacturing

Overcome the purification challenges presented by complex novel formats derived from conventional  antibody structures, including Fab fragments, Fc-fusion proteins, and bispecifics.

Rapid Implementation of Novel Affinity Purification

Discover how a customer was able to rapidly implement antibody affinity resins into their commercial manufacturing process for a next-generation antibody therapeutic. 


eBooks

Quality innovations in monoclonal antibody manufacturing

Discover solutions for common purification, analysis, and quality evaluation challenges when manufacturing modern antibody-derived therapies. 

AAV Purification and Scale-Up

Explore innovative solutions that surmount technical hurdles and enhance downstream processes, producing high product yield at lower costs.  {Image needs to be provided}

Purification Solutions for Therapeutic Antibodies

Learn about innovative purification tools to help maximize productivity of downstream processing of traditional and complex antibodies therapeutics.


Posters

Upgrade Monoclonal Antibody Purification Workflow with a New Source of Protein A Resin

Review application data of our new Protein A resin designed to help improve the productivity and efficiency of your antibody purification process.

Accelerating antibody drug development with subdomain-specific affinity chromatography

Explore application data of our subdomain-specific affinity portfolio developed to address purification challenges with novel antibody molecules.


Webinars

Beyond Standard Protein A Resin: Establishment of an Improved DSP Affinity Platform Step for Monoclonal Antibodies

Gain insight into the process design and optimization for novel and affinity chromatography in a monoclonal antibody platform.

Innovation of Novel Purification Strategies: A Case Study of Clusterin Scavenger Resins

Learn about a scavenging clusterin, a common protein found in monoclonal antibody manufacturing, and topics such as the platform process for generating specific VHH antibody-based ligands

Novel Purification Approaches to Streamline Manufacturing of Antibody-based Therapeutics

Discover our complete portfolio of innovative affinity capture and polish solutions to help you develop novel antibody molecules such as Fab fragments, Fc-fusion proteins and bi-specific antibodies.

The Way Forward in Antibody Therapeutics

See how antibody subdomain-specific affinity chromatography can improve the productivity of antibody therapeutics purification workflows.