Luciferase Detection Instrumentation Guide | Thermo Fisher Scientific

Luciferase reporter assays are widely used because of their sensitive detection capacity and broad dynamic range. While many companies make instruments to detect and measure luciferase activity, identifying the right instrument for you can be difficult because of their high degree of feature variability. We therefore gathered salient information about many of the instruments available to date so we could provide a resource to help you compare the different instruments, their type, spectral resolution compatibility, filter size, and injectors (if any).

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Use the search field to filter the table for specific makes, models, or other instrument characteristics.

Instrument model names are trademarks of their respective makers. Table updated: July 13, 2012.

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Make	Model	Instrument type	Capable of spectral resolution	Filter size	Injectors
ATTO	Luminescencer Octa	Single tube luminometer	Yes	Built in	Yes—Max. 1
ATTO	Phelios	Luminometer plate reader	Yes	Built in	Yes—1 or 2
ATTO	Kronos Dio	Luminometer, real time culture	Yes	Built in	No
ATTO	LumiFLspectrocapture	Multimodal, single sample, cooled CCD	Yes	N/A	Yes
Berthold Technologies	Mithras LB 940	Multimodal plate reader	Yes	25 mm	Yes—Max. 4
Berthold Technologies	TriStar LB 941	Multimodal plate reader	Yes	25 mm	Yes—Max. 4
Berthold Technologies	TriStar2 LB 942	Multimodal plate reader	Yes	25 mm	Yes—Max. 3
Berthold Technologies	CentroLIA LB 961	Luminometer	No	N/A	No
Berthold Technologies	CentroLIApc LB 962	Luminometer	No	N/A	No
Berthold Technologies	Centro LB 960	Luminometer	No	N/A	Yes—Max. 3
Berthold Technologies	Centro XS3 LB 960	Luminometer	No	N/A	Yes—Max. 3
Berthold Technologies	CentroPRO LB 962	Luminometer	No	N/A	No
Berthold Technologies	Junior LB 9509	Portable tube luminometer	No	N/A	No
Berthold Technologies	Lumat LB 9507	Single tube luminometer	No	N/A	Yes
Berthold Technologies	Lumat 3	Single tube luminometer	No	N/A	Yes—2
Berthold Technologies	AutoLumat LB 953	Multi-tube luminometer	No	N/A	Yes—Max. 3
BioTek	Synergy Neo	Multimodal plate reader	Yes	No info	Yes—Max. 2
BioTek	Synergy H4	Multimodal plate reader	Yes	17.5 mm	Yes—Max. 2
BioTek	Synergy 2	Multimodal plate reader	Yes	17.5 mm	Yes—Max. 2
BioTek	Synergy 2 SL	Luminometer	No	N/A	Yes—Max. 2
BioTek	Synergy Mx	Luminometer or multimodal	Limited - monochronometer based	Built in	Yes—Max. 2
BioTek	Synergy HT	Multimodal plate reader	Yes	17.5 mm	Yes—Max. 2
BioTek	FLx800	Multimodal plate reader	Yes	17.5 mm	Yes—Max. 1
BioTek	Synergy H1m	Multimodal plate reader	Yes - filter module	No info	Yes—Max. 2
BioTek	Synergy H1	Multimodal plate reader	Yes - w/ filter module	17.5 mm	Yes—Max. 2
BMG LabTech	PHERAstar FS	HTS multimodal	Yes	12 or 15 mm	Yes—Max. 2
BMG LabTech	PHERAstar Plus	HTS multimodal	Yes	12 or 15 mm	No
BMG LabTech	FLUOstar Omega	Multimodal	Yes	12 or 15 mm	Yes—Max. 2
BMG LabTech	POLARstar Omega	Multimodal	Yes	12 or 15 mm	Yes—Max. 2
BMG LabTech	NOVOstar	Multimodal	No	N/A	Yes—Max. 2 + integrated pipettor system
BMG LabTech	FLUOstar OPTIMA	Multimodal	Yes	12 or 15 mm	Yes—Max. 2
BMG LabTech	POLARstar OPTIMA	Multimodal	Yes	12 or 15 mm	Yes—Max. 2
BMG LabTech	LUMIstar Omega	Luminometer	Yes	12 or 15 mm	Yes—Max. 2
BMG LabTech	LUMIstar OPTIMA	Luminometer	Yes	12 or 15 mm	Yes—Max. 2
BMG LabTech	FLUOstar OPTIMA FL	Multimodal	Yes	12 or 15 mm	Yes—Max. 2
Hamamatsu	FDSS/µCell	Kinetic plate reader	No info	No info	Yes—whole plate dispenser (96 or 384 well)
Hamamatsu	FDSS7000EX	High throughput screening system	Yes (optional feature)	No info	Yes—several dispensing options
Hamamatsu	FDSS/RayCatcher	Luminometer plate reader	Yes (optional feature)	No info	No
Harta Instruments	MicroLumi L2	Luminometer (for field use)	No info	No info	No info
Hidex	Plate Chameleon V	Microplate reader, modular	Yes - Using Filtered Detection Mode	25 mm	Yes—Max. 2
Hidex	Triathler	Luminometer or multilabel tester	No	N/A	Yes—Max. 1
Molecular Devices	FlexStation 3	Multimodal	Limited - monochronometer based	N/A	Pipettor - 8 or 16 channel
Molecular Devices	SpectraMax Paradigm	Multimodal, HTS	Yes, but may require custom filter cartridge	Cartridge-based	No
Molecular Devices	SpectraMax M5e	Multimodal	Limited - monochronometer based	N/A	No
Molecular Devices	SpectraMax M5	Multimodal	Limited - monochronometer based	N/A	No
Molecular Devices	SpectraMax M4	Multimodal	Limited - monochronometer based	N/A	No
Molecular Devices	SpectraMax M3	Multimodal	Limited - monochronometer based	N/A	No
Molecular Devices	SpectraMax M2e	Multimodal	Limited - monochronometer based	N/A	No
Molecular Devices	SpectraMax M2	Multimodal	Limited - monochronometer based	N/A	No
Molecular Devices	FilterMax F3	Multimodal	Yes - but only detects to 650 nm	No info	No
Molecular Devices	FilterMax F5	Multimodal	Yes	No info	No
Molecular Devices	SpectraMax L	Luminometer	Yes - but only detects to 630 nm	No info	Yes—Max. 2
Perkin Elmer	EnSpire	Multilabel	Limited - monochronometer based	N/A	Yes—Max. 2
Perkin Elmer	EnVision	Multilabel	Yes	No info	Yes—Max. 2
Perkin Elmer	EnVision Xcite	Multilabel	Yes	No info	Yes—Max. 2
Perkin Elmer	Victor X Light	Luminometer	Yes	25.4 mm	Yes—Max. 4
Perkin Elmer	Victor X2	Multilabel	Yes	25.4 mm	Yes—Max. 4
Perkin Elmer	Victor X3	Multilabel	Yes	25.4 mm	Yes—Max. 4
Perkin Elmer	Victor X4	Multilabel	Yes	25.4 mm	Yes—Max. 4
Perkin Elmer	Victor X5	Multilabel	Yes	25.4 mm	Yes—Max. 4
Perkin Elmer	Victor3	Multilabel	Yes	No info	Yes—Max. 4
Perkin Elmer	Victor3 V	Multilabel	Yes	No info	Yes—Max. 4
Perkin Elmer	MicroBeta2 LumiJET	Scintillation and luminescence	No	N/A	Yes—1 or 2 per detector, 1 to 12 detectors
Perkin Elmer	TopCount NXT	Scintillation and luminescence	No	N/A	No
Perkin Elmer	ViewLux CCD Imager	Multimodal HTS	Yes	60 mm	No
Promega	GloMax-Multi+ w/ Instinct	Multimodal	No	N/A	Yes—Max. 2
Promega	GloMax-Multi	Multimodal	No	N/A	Yes—Max. 2
Promega	GloMax-96	Luminometer	No	N/A	Yes—Max. 2
Promega	GloMax-20/20	Luminometer (w/ optional fluorescence module)	No	N/A	Yes—Max. 2
Promega	GloMax-Multi Jr	Multimodal	No	N/A	No
Stratec	Solaris	Luminometer	No	N/A	Yes—Max. 3
Stratec	SL 300	Luminometer	No info	No info	Pipetting System
Tecan	Infinite F200 PRO	Multimodal	Yes, but filters cannot be changed by customer	12.5 mm	Yes—Max. 2
Tecan	Infinite F500	Multimodal	Yes, but filters cannot be changed by customer	12.5 mm	Yes—Max. 2
Tecan	Infinite M200 PRO	Multimodal	Limited - monochronometer based	N/A	Yes—Max. 2
Tecan	Infinite M1000 PRO	Multimodal	Limited - monochronometer based	N/A	Yes—Max. 2
Thermo Scientific	Varioskan Flash	Multimodal	Yes	24.5 - 25.4 mm	Yes—Max. 3
Thermo Scientific	Appliskan	Multimodal	Yes	25.4 mm	Yes—Max. 2
Thermo Scientific	Fluoroskan Ascent FL	Multimodal	Yes	15 mm	Yes—Max. 3
Thermo Scientific	Luminoskan Ascent	Luminometer	Yes	15 mm	Yes—Max. 3
TiterTek Berthold	MPL1	Luminometer	No	N/A	No
TiterTek Berthold	MPL2	Luminometer	No	N/A	No
TiterTek Berthold	Orion L	Luminometer	No	N/A	Yes—Max. 2
TiterTek Berthold	Orion II	Luminometer	No	N/A	Yes—Max. 4
TiterTek Berthold	Sirius	Single tube luminometer	No	N/A	Yes—Max. 2
TiterTek Berthold	Sirius L	Single tube luminometer	No	N/A	Yes—Max. 2
TiterTek Berthold	FB12	Single tube luminometer	No	N/A	No
TiterTek Berthold	Smart Line - Smart Card	Single tube luminometer	No	N/A	Yes—Max. 2

For Research Use Only. Not for use in diagnostic procedures.