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Platelet-Derived Growth Factor (PDGF) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets and is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication. The synthesis of PDGF can be induced by IL-1, IL-6, TNF-alpha, TGF-beta and EGF.
Becaplermin; c-sis; H-PDGF-AB; IBGC5; PDGF A-chain; PDGF subunit A; PDGF subunit B; PDGF, B chain; PDGF1; PDGF-1; PDGF2; PDGF-2; Pdgfa; PDGF-A; PDGFAB; PDGFB; PDGF-B; platelet derived growth factor subunit A; platelet derived growth factor subunit B; platelet derived growth factor, alpha; platelet derived growth factor, B polypeptide; platelet-derived growth factor 2; platelet-derived growth factor A chain; platelet-derived growth factor A-chain; platelet-derived growth factor alpha chain; platelet-derived growth factor alpha polypeptide; Platelet-derived growth factor B chain; platelet-derived growth factor beta polypeptide; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog); platelet-derived growth factor subunit A; Platelet-derived growth factor subunit B; platelet-derived growth factor, beta polypeptide (oncogene SIS); proto-oncogene c-Sis; SIS; SSV
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