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The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known.
AY465109; Gm1020; NICE-2; protein S100-A15A; Protein S100-A7; protein S100-A7A; PSOR1; Psoriasin; psoriasin 1; S100 calcium binding protein A15; S100 calcium binding protein A7; S100 calcium binding protein A7A; S100 calcium binding protein A7-like 1; S100 calcium-binding protein A15; S100 calcium-binding protein A15A; S100 calcium-binding protein A7; S100 calcium-binding protein A7 (psoriasin 1); S100 calcium-binding protein A7A; S100 calcium-binding protein A7-like 1; S100A15; S100a15a; S100a17l1; S100A7; S100a7a; S100A7c; S100A7f; S100A7L1
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