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This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.
68kDa; AI181842; AI747162; beta ig-h3; Beta-ig; beta-ig-h3; betaig-h3; BIGH3; Big-h3; CDB1; CDG2; CDGG1; CSD; CSD1; CSD2; CSD3; EBMD; kerato-epithelin; LCD1; MP70; MP78; RGD-CAP; RGD-containing collagen-associated protein; TGFBI; transforming growth factor beta induced; transforming growth factor beta-induced 68kDa; transforming growth factor induced protein; transforming growth factor, beta induced; transforming growth factor, beta induced, 68 kDa; transforming growth factor, beta-induced, 68kD; transforming growth factor, beta-induced, 68kDa; Transforming growth factor-beta-induced protein ig-h3
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