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Transcend TLX TurboFlow UHPLC Systems
Enable fast cleanup of complex matrices for accelerated online sample preparation, lower your laboratory costs, and improve data quality using Thermo Scientific Transcend TLX Systems with TurboFlow technology. These systems use a combination of chromatographic techniques for online sample cleanup to improve LC-MS detection, reduce manual work, and provide higher productivity while the systems' additional channel capabilities improve throughput by up to 400%. Thermo Scientific Aria MX software makes method setup easy and schedules several aspects of the system.
Highlights
Automated sample clean-up
Online sample clean-up minimizes manual sample preparation and facilitates direct sample injection into the LC-MS system for complex sample matrices, including plasma and urine, to save time.
Improved return on investment
Multichannel technology increases throughput two- to four-fold using a single instrument with no need for new method development, accelerating laboratory output and revenue generation.
Extended sample capacity
Sample capacity can be extended from six to twelve 96- or 384- well plates by adding another cool stack to the Thermo Scientific TriPlus RSI autosampler for greater throughput.
Easy setup and system control
Thermo Scientific Aria MX software manages and controls pump operation, valve switching, cleaning, and gradients. Quickly develop methods and run batches of samples while managing multiple LC-MS methods on multiple channels simultaneously. Aria MX software is compatible with Thermo Scientific XCalibur or TraceFinder software.
How does multichannel LC-MS work?
Our multichannel LC system is designed specifically for LC-MS and allows you to run two of the same or two different applications using one mass spectrometer. Two channels run staggered LC-MS analyses, ensuring the mass spectrometer is never idle. The diagram below illustrates the resulting MS signal when running two different applications on the Transcend TurboFlow TLX UHPLC system.
Maximize MS utilization by using two channels with intelligent scheduling to run the second analysis during column reconditioning.
System specifications
The table below provides an overview of the Transcend TurboFlow TLX UHPLC systems specifications for a standard setup. Not all specifications are listed. Specifications may differ based on the specific system components selected. See detailed Component Specifications for more information.
| Category | Transcend TurboFlow TLX UHPLC Systems |
| System pressure, maximum | 1000 bar |
| Flow range | 0-8 mL/min |
| Pump options (default delay volume) | Binary (100 µL) Quaternary (379 µL) |
| Biocompatible | Yes |
| pH range | 2–12, chloride concentration up to 1 mol/L |
| System design | Modular |
| Touchscreen user interface display compatible (optional) | No |
| Solvent monitoring system compatible (optional) | No |
| Customizable gradient delay volume to simplify method transfer | No |
| SmartInject technology for maximum injection precision and improved column lifetime | No |
| Injection volume range | Standard: 0.01-100 µL Optional: up to 10,000 µL |
| Sample cooling | Yes |
Sample capacity (standard) Based on standard 12 mm OD vials (≤ 1.5 mL) |
6 racks that hold 54 vials each |
| Sampler extension available (optional) | Yes, with drawers |
| Column compartment thermostatting | Yes Optional sleeve heater |
Column compartment pre-heater |
Not available |
| Column compartment post-column cooler | Not available |
| Compatible detectors | Mass Spectrometer |
Component specifications
Standard Transcend TurboFlow TLX UHPLC systems are made up of the following components. Download the associated specifications sheet for more detail on each component.
| Transcend TLX-1 | Transcend TLX-2 |
Transcend TLX-4 | |
Pump
|
and |
and |
and |
Autosampler
|
Triplus RSI | ||
Extended sample capacity (optional)
|
3- or 6-drawer cool stack (optional) |
||
Flow path switching
|
3-valve interface module | 6-valve interface module | 10-valve interface module |
Detectors
|
1 mass spectrometer |
||
For Research Use Only. Not for use in diagnostic procedures.