EVOS S1000 Spatial Imaging System for Multiplexed Tissue Imaging

The system designed to simplify the tissue imaging process

Simply perform spatial biology tissue imaging by utilizing a multiplex approach to simultaneously detect biomarkers through fluorescence and brightfield.

 

The Invitrogen EVOS S1000 Spatial Imaging System is only available in participating countries and regions including US, Canada, and Europe in 2024.

Features

The Invitrogen EVOS S1000 Spatial Imaging System can complete the imaging process quickly to its capability to generate a fully stitched, unmixed, multiplexed image for multiple samples. It offers a single operating software that simplifies the imaging process, allowing users to effortlessly navigate through each step required to acquire a multiplex image. This intuitive interface makes it easy for users to quickly become familiar with the system and efficiently perform their experiments, regardless of their level of expertise.

Features include:
  • Easily multiplex up to 8 targets plus DAPI in a single round
  • Use spectral fluorescence, transmitted brightfield, and phase and color brightfield in one instrument
  • Quickly scans multiple tissues on a single slide, with capacity for 4 whole slides
  • Powerful autofocus, with custom IR laser and software routines
  • Single operating software offers fast overview scans, periscope mode for tissue navigation, spectral unmixing, and whole-slide stitching and imaging
  • Our spectral solution reduces fluorescence crosstalk and produces highly accurate data

A spatial imaging system that is simpler to use and designed for high-resolution data

Feedback about the EVOS S1000 Spatial Imaging System provided from Jennifer Gantchev, PhD.

Simplified tissue imaging workflow

Unlike existing technologies that can take several days to weeks, the EVOS S1000 instrument can complete the imaging process within several hours, with the greatest time savings found in its capability to generate a fully stitched, unmixed, multiplexed image for multiple samples. With the EVOS S1000 Spatial Imaging System, you have the flexibility to use a variety of label technologies, allowing you to select and utilize your preferred antibodies, secondaries, and reagents. The instrument outputs OME-TIFF files that are compatible with any third-party analysis software such as Halo and QuPath.

The Spatial Biology Multiplex Workflow incorporates the EVOS S1000 Spatial Imaging System that multiplexes more biomarkers with the use of spectral unmixing. This software reduces autofluorescence interference and fluorescence crosstalk for more accurate data.

Tissue labeling antibodies, secondaries, and reagents

Primary conjugated antibodies

Detect numerous targets simultaneously by multiplexing primary conjugated antibodies to fluorophores. These antibodies have been tested on tissue samples and come in formats compatible with the EVOS S1000 Spatial Imaging System and other microscopy platforms.

ReadyLabel Antibody Labeling Kits

Label your unconjugated antibodies with ReadyLabel Antibody Labeling Kits. This process takes 1 hour from start to finish.

Aluora Spatial Amplification Kits

Detect up to 8 targets simultaneously in one tissue sample with Aluora Spatial Amplification Kits. These kits combine bright Aluora dyes with enzyme-mediated signal amplification to help overcome autofluorescence in the detection of rare targets.  

ViewRNA ISH Tissue Assay

Detect multiple RNA targets within tissue sample. The kit provides exceptional sensitivity and allows single-molecule detection of up to four RNA targets simultaneously.

Resources

Imaging Protocol Handbook

Read and use trusted protocols for many types of imaging including 3D staining, multiplexing ISH in tissue, and other spatial biology protocols.

Spatial Biology Resource Center

Find resources including webinars, conference posters, protocols, guides, handbooks, and publications to start your multiplex experiments.

For Research Use Only. Not for use in diagnostic procedures.