Nalgene Containment Solutions

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Empowering bioprocessing excellence

With 75 years of trusted single-use bioprocessing containment solutions, the Nalgene portfolio is designed with precision and innovation. Our products provide excellent containment and protection for your valuable biopharmaceutical processes.

We offer a comprehensive product portfolio of single-use bioprocessing solutions, so you can choose the products that meet your specific needs and budget. Rest assured in our product features and the peace of mind that comes from using a single supplier with a global supply chain.

Nalgene bottles and carboys

Nalgene production bottles and carboys offer leakproof* storage for sensitive liquids, buffers, media, and more. They are available in PC, PETG, PP, LDPE, HDPE, FEP, and PFA in volumes ranging from 5 mL to 50 L. Extensive regulatory documentation helps ensure that the products meet your demanding biotechnology requirements and can easily integrate into your processes.

Be particular in choosing the right solution

Application	Standard	Low particulate	Ultralow particulate
Ideal for storage and sampling of active pharmaceutical ingredients and bulk intermediates
Ideal for storage and/or transportation of pH-sensitive materials, such as biological drug substance
Key features
Sterile and non-sterile options
Manufactured from a high-quality resins
Leakproof closures*
Triple-layer packaging (two heat seals and one carton liner)
Produced in an ISO 7 clean room
Compliant with USP <788>
Certified to 1/3 of the allowable USP <788> particulate limits
Washed with WFI (water for injection)**
Inspected, assembled, and packaged in ISO 5 (Class 100) clean rooms with ISO 4 (Class 10) hoods and full gowning for operators

* Our guarantee for a leakproof seal is subject to our standard product warranty, as set forth in the Thermo Fisher Scientific Terms and Conditions of Sale. Our products are leakproof under use with our required specifications at ambient temperature and pressure when used with their corresponding closures, when handled properly and secured by the user properly. However, to ensure safe usage, customers are advised to test our containers and closures under conditions of their planned application.

** Not all Platinum Certified Clean ultralow particulate bottles products require WFI wash to meet particulate claims

Take a look at the Nalgene portfolio

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Nalgene bioprocessing containment accessories

Whether you are looking for reliable closures to secure your containers or durable tubing for various applications, we have got you covered. Choose from a wide range of Thermo Scientific Nalgene closures and tubing.

Nalgene bottle and carboy assembly systems

Fluid transfer systems play an important role in bioprocessing but can easily cause inefficiencies; multiple components need to be sourced, purchased, inventoried, and assembled. Our fit-for-purpose Thermo Scientific Nalgene Bottle and Carboy Assembly Systems are designed to reduce the burden of managing individual components and to enabled in-house system assembly and validation.

Available in a variety of resins and sizes

Polycarbonate (PC) 
Polyethylene terephthalate glycol (PETG)
High-density polyethylene (HDPE)
125 mL to 20 L

Closures and components to meet your needs

Configuration available with 2- or 3-port closure
Comprehensive list of components available for process-specific assembly

Supply assurance and risk mitigation

Global manufacturing network, with in-region manufacturing built to ensure supply chain resiliency, redundancy, and excellent service

Standard Single-Use Bottle Assembly Systems

Easy-to-order configured solutions include Nalgene bottles with preconfigured cap sets and are delivered gamma-irradiated for use right out of the package.
Available off the shelf < 1 week

Download datasheet >

Customized Single-Use Bottle Assembly Systems

Featuring the BioTitan Retention Device, designed to provide superior universal retention that minimizes the risk of leakage and failure at the connection point***
Available off the shelf < 6 weeks

Download infographic >

Customized Single-Use Carboy Assembly Systems

Featuring the BioTitan Retention Device
Available off the shelf < 6 weeks
Available in multiple sizes: 10 L, 15 L, 20 L, 25 L, 50 L
Custom low particulate washing available to help secure your substances with ultralow particulate options

Ask a specialist about how a custom carboy assembly can meet your application needs.

Contact a specialist >

*** No leaks reported since 2021 launch as of the publishing this web page May 2024

View full portfolio of products

Nalgene glassware and vials

	Low particulate Choose from a large range of standard particle-certified containers assembled to contain as few as 5 particles per milliliter >0.5 microns Non-standard containers may be custom cleaned on request
	Total Organic Carbon (TOC) Glassware Simplify and reduce the cost of cleaning validations. Low background is perfect for preparation and storage of standards. TOC-certified containers are available in several sizes, including the popular 40 mL autosampler vials–cleaned, certified, and ready-to-use TOC water and other specialty waters are packaged in precleaned amber glass containers and are ideal for dilution of TOC testing samples
	Sterile vials Put your trust in proven products developed by industry experts for performance, usability, and cost-effectiveness Glass vials and other containers are offered in a variety of sizes that have been specially prepared to meet endotoxin levels of less than 0.06 EU/mL
	Silanized glassware Surface deactivation treatments such as silanization may play an important role in preserving the integrity of certain materials or extracts stored in glass containers It also helps to avoid alkalinization of contents which may occur as carbonates leach from the glass with normal weathering

Low particulate washing services

We understand the critical importance of maintaining clean and contaminant-free containers and component parts in the biopharma and vaccine industries. Our cleaning service offers unmatched expertise and state-of-the-art facilities to ensure the highest standards of cleanliness and compliance.

Comprehensive cleaning solutions: Our cleaning service is designed to meet the unique needs of CMO/CDMO and biotech companies. We have the capability to clean glass or plastic containers, stoppers, closures, or other component parts up to 50 L in size.
Quality assurance: Our cleaning processes are backed by rigorous quality control measures to ensure that every cleaned item meets the highest standards of cleanliness and regulatory compliance.
Risk mitigation: Our cleaning service helps reduce the risk of contamination, thereby safeguarding the integrity and safety of your biopharma and vaccine products.
Increased efficiency: Outsourcing your cleaning needs to us enables you to focus on your core operations, improving overall efficiency and productivity.

Download brochure

Nalgene tanks and tank liners

Designed for easy installation and maintenance, our Nalgene tanks and tank liners are cost-effective solutions that provide long-lasting performance, helping you optimize your fluid storage processes and minimize operational risks.

Nalgene containment solutions selection guide

Looking for reliable containment to protect your high-quality products in storage, transport, and sampling? Made from high-quality resins, Nalgene production bottles and carboys offer leakproof* storage for sensitive liquids, buffers, media, and more. Nalgene containers help ensure your substances stay secure, with low and ultralow particulate options available, addressing particulate level (USP <788>), endotoxin level, and sterility requirements.

Choose the Nalgene containers that best fit your applications needs by browsing our selection guide