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Liquid Products for Bioprocessing
Let us handle your bulk liquids so you can focus on what matters most to you
For over 50 years, production facilities have turned to our trusted Gibco media, feeds, buffers, and bioprocessing liquids to enhance product performance. Our products are designed to meet your specifications including flexible BioProcess Containers (BPCs) in the size of your choice from 1 L to 1,000 L. By combining our standard and custom products with our worldwide supply chain distribution centers we can offer you superior solutions for your process with the continuity of having one consistent supply partner.
Overview of our bioprocessing liquid capabilities for custom and catalog products
| Catalog | Custom | |
| Validated shipping configurations from bottles to bioprocess containers | PET BOXY bottles: 100 mL, 500 mL, 1,000 mL | 50 mL to 1,000 L |
| Bioprocess containers (BPCs): 1 L, 5 L, 10 L, 20 L, 50 L, 100 L, 200 L, 500 L, 1,000 L | ||
| Catalog formulation in the film of your choice | Thermo Scientific Aegis5-14 film | Aegis5-14 film |
| Thermo Scientific CX5-14 film | CX5-14 film | |
| ASI 26/77 film | ASI 26/77 film | |
| Batch/lot sizes | Stainless steel tank sizes of 200 L to 10,000 L | Best-in-class liquid formulation with capacity and processes to handle small- and large-volume liquids |
| Portable Nalgene tanks 10–400 L | Assurance of supply via two-continent redundant manufacturing | |
| AOF 5,000L and 10,000 L tanks and suites | A range of liquid formats to meet customer needs (concentrates, 1x liquids, bottles and bags) | |
| One formulation per room | ||
| Validated CIP/COP processes | ||
| Gibco media, feeds, and supplements | CD OptiCHO | |
| Dynamis | ||
| CD CHO | ||
| EfficientFeed A+/B+/C+ | ||
| FunctionMAX Titer Enhancer | ||
| Bioprocess buffer | Water for Injection (WFI) | |
| Media, feeds, and supplements | Your custom formulation or Gibco brand solutions | |
| Bioprocess buffers | Your custom formulation for upstream (PBS, glucose, HBSS) and downstream buffers (NaOH, HCl, titration, equilibration, binding, elution buffers) as well as cleaning and sanitizing process liquids (WFI, EDTA, HCl) | |
| Value-added customer service | Dedicated Client Project Managers will oversee each custom project | |
| High standard quality processes | Detailed documentation |
Unique global footprint with our manufacturing and warehousing capabilities
With continual investment in multiple global plant expansions, Thermo Fisher Scientific aims to provide seamless customer experiences. Since 2011, we have invested over $38M (USD) to enhance supply security and risk mitigation, offering you peace of mind.
Select any of our integrated global locations and receive long-term supply with minimal production interruptions.
Grand Island, New York
| Paisley, Scotland
|
Harmonization of our manufacturing facilities in the US and Europe is in progress.
- Raw materials—expanding our multi-compendial library for common chemical raw materials and standard bag offerings
- Equipment—continually expanding our liquid capabilities for both AO and AOF requests
- Finished product testing—USP/EP testing available; sterility, endotoxin, conductivity, osmolality, pH, etc.
Access warehousing and logistical services in addition to quality manufacturing. Whether your needs are short-term or long-term, we have storage to suit your production and distribution requirements. Manage your shipping by choosing from temperature-controlled, cold, and ambient-temperature warehouses located all over the globe.
Access increased capacity and capabilities at any of Thermo Fisher Scientific’s global facilities.
Take control of your product delivery
Thermo Fisher Scientific’s supplier qualification program is designed to provide customers with more control over product delivery. We’ve implemented a robust supply risk mitigation strategy to help ensure that our suppliers meet the rigorous standards required to avoid stock-outs and shortages.
Thermo Fisher Scientific enables you to focus on delivering biotherapeutics and vaccines without worrying about costly production interruptions. With an expanded global reach and dual sourcing of raw materials, we’re able to leverage economies of scale and access high-quality resources at the best prices—so you can expect more savings on more options.
To meet current and future customer requirements for insourcing large-volume liquids or bulk liquids, our Grand Island manufacturing facility will adhere to the following standards, supporting consistent performance for each batch:
|
|
Our robust supplier management program helps ensure sourcing from qualified and audited raw material suppliers. We have qualified multiple raw-material sources for risk mitigation and contingency planning purposes. We also offer Animal Origin Free (AOF) manufacturing segregation with single-use liquid management systems. These single-use advantages alleviate cleaning, validation, and cross-contamination concerns.
Custom media, buffers, and process liquid formulations and their packaging
We offer expanded expertise in BPC film for bulk liquids. Get multiple proprietary BPC films in customizable types and sizes—only from Thermo Fisher Scientific.
- CX5-14 and Aegis5-14 films are validated for liquid fills and shipments from Grand Island and Paisley
- Extractables and leachables data package available for each film
- Stability data in progress for common media and buffer liquid in CX5-14 and Aegis films
- Customer-specified stability available as a fee for service
- Continued supply of liquids in existing orders in 9101 and BF1400 BPCs
Liquid container options can be customized by size and configuration. Our Open Architecture component strategy features a library of more than 1,000 qualified components. This allows you to optimize several aspects of the BPC, including support container, chamber size and porting, tubing size and style, and fittings and end treatments.
Global quality system and technical services
Get the support you need with Thermo Fisher Scientific’s Global Quality System and Gibco BioProduction Services. Our experienced professionals are ready to help you take control of any product development or process optimization challenges you may have.
Stability testing
- State-of-the-art analytical laboratory supports your stability testing requirements
- Stability Data Sheet provides a summary of stability test data for model formulations
Technical support
- Extractables and leachables data package available for each type of film, with customized testing available upon request
- Packaging engineers to optimize packaging and shipping configurations for enhanced pre- and post-shipment product integrity
Overview of our bioprocessing liquid capabilities for custom and catalog products
| Catalog | Custom | |
| Validated shipping configurations from bottles to bioprocess containers | PET BOXY bottles: 100 mL, 500 mL, 1,000 mL | 50 mL to 1,000 L |
| Bioprocess containers (BPCs): 1 L, 5 L, 10 L, 20 L, 50 L, 100 L, 200 L, 500 L, 1,000 L | ||
| Catalog formulation in the film of your choice | Thermo Scientific Aegis5-14 film | Aegis5-14 film |
| Thermo Scientific CX5-14 film | CX5-14 film | |
| ASI 26/77 film | ASI 26/77 film | |
| Batch/lot sizes | Stainless steel tank sizes of 200 L to 10,000 L | Best-in-class liquid formulation with capacity and processes to handle small- and large-volume liquids |
| Portable Nalgene tanks 10–400 L | Assurance of supply via two-continent redundant manufacturing | |
| AOF 5,000L and 10,000 L tanks and suites | A range of liquid formats to meet customer needs (concentrates, 1x liquids, bottles and bags) | |
| One formulation per room | ||
| Validated CIP/COP processes | ||
| Gibco media, feeds, and supplements | CD OptiCHO | |
| Dynamis | ||
| CD CHO | ||
| EfficientFeed A+/B+/C+ | ||
| FunctionMAX Titer Enhancer | ||
| Bioprocess buffer | Water for Injection (WFI) | |
| Media, feeds, and supplements | Your custom formulation or Gibco brand solutions | |
| Bioprocess buffers | Your custom formulation for upstream (PBS, glucose, HBSS) and downstream buffers (NaOH, HCl, titration, equilibration, binding, elution buffers) as well as cleaning and sanitizing process liquids (WFI, EDTA, HCl) | |
| Value-added customer service | Dedicated Client Project Managers will oversee each custom project | |
| High standard quality processes | Detailed documentation |
Unique global footprint with our manufacturing and warehousing capabilities
With continual investment in multiple global plant expansions, Thermo Fisher Scientific aims to provide seamless customer experiences. Since 2011, we have invested over $38M (USD) to enhance supply security and risk mitigation, offering you peace of mind.
Select any of our integrated global locations and receive long-term supply with minimal production interruptions.
Grand Island, New York
| Paisley, Scotland
|
Harmonization of our manufacturing facilities in the US and Europe is in progress.
- Raw materials—expanding our multi-compendial library for common chemical raw materials and standard bag offerings
- Equipment—continually expanding our liquid capabilities for both AO and AOF requests
- Finished product testing—USP/EP testing available; sterility, endotoxin, conductivity, osmolality, pH, etc.
Access warehousing and logistical services in addition to quality manufacturing. Whether your needs are short-term or long-term, we have storage to suit your production and distribution requirements. Manage your shipping by choosing from temperature-controlled, cold, and ambient-temperature warehouses located all over the globe.
Access increased capacity and capabilities at any of Thermo Fisher Scientific’s global facilities.
Take control of your product delivery
Thermo Fisher Scientific’s supplier qualification program is designed to provide customers with more control over product delivery. We’ve implemented a robust supply risk mitigation strategy to help ensure that our suppliers meet the rigorous standards required to avoid stock-outs and shortages.
Thermo Fisher Scientific enables you to focus on delivering biotherapeutics and vaccines without worrying about costly production interruptions. With an expanded global reach and dual sourcing of raw materials, we’re able to leverage economies of scale and access high-quality resources at the best prices—so you can expect more savings on more options.
To meet current and future customer requirements for insourcing large-volume liquids or bulk liquids, our Grand Island manufacturing facility will adhere to the following standards, supporting consistent performance for each batch:
|
|
Our robust supplier management program helps ensure sourcing from qualified and audited raw material suppliers. We have qualified multiple raw-material sources for risk mitigation and contingency planning purposes. We also offer Animal Origin Free (AOF) manufacturing segregation with single-use liquid management systems. These single-use advantages alleviate cleaning, validation, and cross-contamination concerns.
Custom media, buffers, and process liquid formulations and their packaging
We offer expanded expertise in BPC film for bulk liquids. Get multiple proprietary BPC films in customizable types and sizes—only from Thermo Fisher Scientific.
- CX5-14 and Aegis5-14 films are validated for liquid fills and shipments from Grand Island and Paisley
- Extractables and leachables data package available for each film
- Stability data in progress for common media and buffer liquid in CX5-14 and Aegis films
- Customer-specified stability available as a fee for service
- Continued supply of liquids in existing orders in 9101 and BF1400 BPCs
Liquid container options can be customized by size and configuration. Our Open Architecture component strategy features a library of more than 1,000 qualified components. This allows you to optimize several aspects of the BPC, including support container, chamber size and porting, tubing size and style, and fittings and end treatments.
Global quality system and technical services
Get the support you need with Thermo Fisher Scientific’s Global Quality System and Gibco BioProduction Services. Our experienced professionals are ready to help you take control of any product development or process optimization challenges you may have.
Stability testing
- State-of-the-art analytical laboratory supports your stability testing requirements
- Stability Data Sheet provides a summary of stability test data for model formulations
Technical support
- Extractables and leachables data package available for each type of film, with customized testing available upon request
- Packaging engineers to optimize packaging and shipping configurations for enhanced pre- and post-shipment product integrity
Easy reordering
Use the Quick Order page for reorders of the same quantity and specifications.
Contact Customer Care
3175 Staley Road
Grand Island, NY 14072
USA
Phone: 800.955.6288
Fax: 800.331.2286
Related resources
Bioprocessing resources
Access a targeted collection of scientific application notes, case studies, posters, white papers and more for bioprocessing: