Sanger Sequencing and Fragment Analysis by CE | Thermo Fisher Scientific

When you can’t afford to get it wrong… capillary electrophoresis enables accurate, unambiguous results for targeted genomic analysis.

Analysis of nucleic acids using capillary electrophoresis (CE) is performed via two methods: Sanger sequencing and fragment analysis. Both provide simple, sample-to-answer workflows for highly accurate sequence interrogation and fast turnaround time.

Sanger sequencing

Gold-standard technology for accurate sequence determination with single-base resolution. Ideal for targeted sequencing and confirmation analysis.

Learn how Sanger sequencing supports various applications:

Download Sanger Sequencing guide ›
Explore the simple Sanger sequencing workflow ›

Fragment analysis

Simple, most time efficient 4-step method for multiplexed detection of pathogens, variants, SNPs or size analysis.

Take DNA analysis further with fragment analysis applications:

Download Fragment Analysis Applications guide ›
Explore the 4-step fragment analysis workflow ›

Instruments and kits for genetic analysis

Applied Biosystems capillary electrophoresis products provide end-to-end workflow solutions for Sanger sequencing and fragment analysis and include genetic analyzers, reagents, and software.

CE instrument family on ATGC blue background

Low to high sample throughput genetic analyzers

Find your instrument ›

Software solutions for viewing and interpreting CE results

Find software for your needs ›

Reagents and kits for capillary electrophoresis

Get them here ›

Capillary electrophoresis applications

Blue ATGC pattern with human head and DNA pattern

Explore all fragment analysis applications ›

Resources

New to capillary electrophoresis? Learn more about these technologies and how scientists are using them to get answers to complex and challenging questions.

For education and application see our CE training resources,learning center, and publications.