HPLC and UHPLC Columns

Overview

We've got a column for that!

Solve your chromatography challenges with our extensive portfolio of HPLC and UHPLC columns designed to meet all of your separation needs. Bringing you a 40-year legacy of innovation, Thermo Scientific (U)HPLC columns offer an unmatched variety of chemistries, from the most popular C18 phases, to innovative mixed-mode chemistries, to the broadest range of solid core columns on the market, and more. We design our columns with everything you expect from a high-quality (U)HPLC column: high resolution, enhanced sensitivity, faster analysis, consistent performance, long column lifetime, and reproducibility. Each of our column types is available in a range of particle sizes and column formats so you can select the column best suited to your workflow.

How are several methods to identify which column is best for you:

Use our HPLC Column Selection Guide
Browse our column category pages to learn about our recommended columns
Contact a representative

All HPLC and UHPLC Columns

HPLC and UHPLC column categories

Low-flow (U)HPLC columns

For your bottom-up, middle down and top-down proteomics research applications. Thermo Scientific nano-, capillary-, and micro-flow columns offer excellent sensitivity and resolution. Find your favourite format amongst our EASY-Spray HPLC Columns, double nanoViper HPLC Columns, and µPAC HPLC Columns.

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Small molecule (U)HPLC columns

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Biomolecule (U)HPLC columns

Analysis of biopharmaceutical therapeutic products demands the use of high quality HPLC and UHPLC columns to achieve high quality results. Read more about Thermo Scientific DNAPac, MAbPac and Propac series and find the right column for your biopharmaceutical analysis.

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Reversed phase (U)HPLC columns

HILIC (U)HPLC columns

Mixed-mode HPLC columns

Application specific HPLC columns

Preparative HPLC columns

HPLC guard columns, cartridges, and accessories

HPLC column selection guide

3 ways to search

Find an equivalent column to the one you’re using now

Find the best column for your USP method

Find the right column for your new method

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Resources

Biopharmaceutical Analysis via (U)HPLC Learning Center

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Understanding the Diversity in HPLC Chromatography Chemistries

In this on-demand webinar, learn about the best HPLC stationary phase chemistries for different sample types, understand the benefits unique selectivity offers to improve resolution in your sample matrices, and identify the different phase options available, facilitating efficient method development and eliminating the guess work from choosing an HPLC column.

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