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LOADING
See other TP53 SIRNA Assays ›
Gene Symbol:
TP53
Gene Name:
tumor protein p53
Gene Aliases:
BCC7, LFS1, P53, TRP53
Chromosome Location:
Chr.17: 7668402 - 7687550 on Build GRCh38
UniGene ID:
Hs.437460
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID
2533
Purification
HPLC
Standard
In-Vivo Ready
Size
5 nmol
20 nmol
20 nmol
Cy3 | 20 nmol
FAM-MGB | 20 nmol
40 nmol
40 nmol
100 nmol
250 nmol
250 nmol
1 umol
10 umol
5 nmol
20 nmol
20 nmol
Cy3 | 20 nmol
FAM-MGB | 20 nmol
40 nmol
40 nmol
100 nmol
250 nmol
250 nmol
1 umol
10 umol
5 nmol
20 nmol
20 nmol
Cy3 | 20 nmol
FAM-MGB | 20 nmol
40 nmol
40 nmol
100 nmol
250 nmol
250 nmol
1 umol
10 umol
Availability
Inventoried
Catalog #
AM16708
Price
Your Price
Online offer:
Check your price ›
Add To Cart
Genomic Map
siRNA Details
More Information
Genomic Map
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siRNA Details
Gene Symbol: TP53
Interrogated Sequence
Translated Protein
Targeted Exon(s)
siRNA Location
IMAGE Clone ID
RefSeq
NM_000546.5
NP_000537.3
6
805
NM_001126112.2
NP_001119584.1
6
802
NM_001126113.2
NP_001119585.1
6
805
NM_001126114.2
NP_001119586.1
6
805
NM_001126115.1
NP_001119587.1
2
485
NM_001126116.1
NP_001119588.1
2
485
NM_001126117.1
NP_001119589.1
2
485
NM_001126118.1
NP_001119590.1
5
922
NM_001276695.1
NP_001263624.1
6
805
NM_001276696.1
NP_001263625.1
6
805
NM_001276697.1
NP_001263626.1
2
485
NM_001276698.1
NP_001263627.1
2
485
NM_001276699.1
NP_001263628.1
2
485
NM_001276760.1
NP_001263689.1
6
805
NM_001276761.1
NP_001263690.1
6
802
GenBank mRNA
AB082923.1
-
6
666
AF307851.1
-
6
738
AK225838.1
-
6
743
AK297462.1
-
7
670
AK297927.1
-
7
715
AK303277.1
-
5
861
AK312568.1
-
6
747
AM076970.1
-
5
570
AM076971.1
-
5
603
AM076972.1
-
5
603
AY429684.1
-
5
603
BC003596.1
-
6
723
3544714
BT019622.1
-
5
603
DQ186648.1
-
6
735
DQ186649.1
-
6
735
DQ186650.1
-
2
481
DQ186651.1
-
2
481
DQ186652.1
-
2
481
DQ191317.1
-
6
792
DQ263704.1
-
5
603
DQ286964.1
-
6
737
DQ648884.1
-
5
403
DQ648885.1
-
3
279
EF101867.1
-
5
570
EF101868.1
-
5
603
EF101869.1
-
5
603
JN214348.1
-
5
648
JN601513.1
-
5
603
JN601514.1
-
5
603
JN601515.1
-
5
603
JN601516.1
-
6
577
JN900492.1
-
5
911
JQ026207.1
-
5
593
JQ026208.1
-
5
598
JQ026209.1
-
5
603
JQ026210.1
-
5
603
JQ694049.1
-
5
626
JQ694050.1
-
5
626
JQ694051.1
-
5
626
KC820708.1
-
2
98
KC820709.1
-
2
98
KC820710.1
-
2
98
KC820711.1
-
2
98
KC820712.1
-
2
98
KC820713.1
-
2
98
KC820714.1
-
2
98
KC820715.1
-
2
98
KC820716.1
-
2
98
KC820717.1
-
2
98
KC820718.1
-
2
98
KC820719.1
-
2
98
KC820720.1
-
2
98
KC820721.1
-
2
98
KC820722.1
-
2
98
KC820723.1
-
2
98
KC820724.1
-
2
98
KC820725.1
-
2
98
KC820726.1
-
2
98
KC820727.1
-
2
98
KC820728.1
-
2
98
KC820729.1
-
2
98
KC820730.1
-
2
98
KC820731.1
-
2
98
KC820732.1
-
2
98
KC820733.1
-
2
98
KC820734.1
-
2
98
KC820735.1
-
2
98
KC820736.1
-
2
98
KC820737.1
-
2
98
KC820738.1
-
2
98
KC820739.1
-
2
98
KC820740.1
-
2
98
KC820741.1
-
2
98
KC820742.1
-
2
98
KC820743.1
-
2
98
KC820744.1
-
2
98
KC820745.1
-
2
98
KC820746.1
-
2
98
KC820747.1
-
2
98
KC820748.1
-
2
98
KC820749.1
-
2
98
KC820750.1
-
2
98
KC820751.1
-
2
98
KC820752.1
-
2
98
KC820753.1
-
2
98
KC820754.1
-
2
98
KC820755.1
-
2
98
KC820756.1
-
2
98
KC820757.1
-
2
98
KC820758.1
-
2
98
KC820760.1
-
2
98
KC820761.1
-
2
98
KC820762.1
-
2
98
KC820763.1
-
2
98
KC820764.1
-
2
98
KC820765.1
-
2
98
KC820766.1
-
2
98
KC820767.1
-
2
98
KC820768.1
-
2
98
KC820769.1
-
2
98
KC820770.1
-
2
98
KC820771.1
-
2
98
KC820772.1
-
2
98
KC820773.1
-
2
98
KC820774.1
-
2
98
KC820775.1
-
2
98
KC820776.1
-
2
98
KC820777.1
-
2
98
KC820778.1
-
2
98
KC820779.1
-
2
98
KC820780.1
-
2
98
KC820781.1
-
2
98
KC820782.1
-
2
98
KC820783.1
-
2
98
KC820784.1
-
2
98
KC820785.1
-
2
98
KC820786.1
-
2
98
M14694.1
-
6
728
M14695.1
-
6
724
X01405.1
-
3
304
X02469.1
-
6
738
X60010.1
-
5
602
X60011.1
-
5
603
X60012.1
-
5
603
X60013.1
-
5
603
X60014.1
-
5
603
X60015.1
-
5
603
X60016.1
-
5
603
X60017.1
-
5
603
X60018.1
-
5
603
X60019.1
-
5
603
X60020.1
-
5
603
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More Information
Other Species Targeted
This siRNA also targets the following transcripts in Rat: XM_003749209.
Panther Classification:
Molecular Function -
P53-like transcription factor
Gene Ontology Categories:
Function(s)
Process(es)
negative regulation of transcription from RNA polymerase II promoter
DNA strand renaturation
base-excision repair
nucleotide-excision repair
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein complex assembly
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
ER overload response
cell cycle arrest
Ras protein signal transduction
multicellular organism development
cell aging
protein localization
cell proliferation
negative regulation of cell proliferation
determination of adult lifespan
response to X-ray
response to gamma radiation
positive regulation of gene expression
viral process
protein sumoylation
cell differentiation
negative regulation of cell growth
DNA damage response, signal transduction by p53 class mediator
positive regulation of histone deacetylation
chromatin assembly
mitotic G1 DNA damage checkpoint
positive regulation of protein oligomerization
cellular response to UV
cellular response to drug
cellular response to glucose starvation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
entrainment of circadian clock by photoperiod
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of neuron apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
response to antibiotic
positive regulation of protein export from nucleus
regulation of mitochondrial membrane permeability
negative regulation of fibroblast proliferation
circadian behavior
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of helicase activity
protein tetramerization
negative regulation of telomerase activity
positive regulation of thymocyte apoptotic process
positive regulation of cell cycle arrest
cellular response to hypoxia
cellular response to ionizing radiation
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of release of cytochrome c from mitochondria
replicative senescence
oxidative stress-induced premature senescence
intrinsic apoptotic signaling pathway
oligodendrocyte apoptotic process
positive regulation of execution phase of apoptosis
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
regulation of signal transduction by p53 class mediator
regulation of cell cycle G2/M phase transition
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
positive regulation of reactive oxygen species metabolic process
positive regulation of intrinsic apoptotic signaling pathway
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter sequence-specific DNA binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protease binding
p53 binding
DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
copper ion binding
protein binding
ATP binding
transcription factor binding
zinc ion binding
enzyme binding
protein kinase binding
protein phosphatase binding
receptor tyrosine kinase binding
ubiquitin protein ligase binding
histone acetyltransferase binding
identical protein binding
sequence-specific DNA binding
protein self-association
transcription regulatory region DNA binding
protein heterodimerization activity
protein N-terminus binding
chaperone binding
protein phosphatase 2A binding
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