Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign in
Don't have an account ?
Create Account
Products
Antibodies
Cell Culture Media
Chemicals
Chromatography Columns and Cartridges
Lab Equipment
Lab Plasticware and Supplies
Microplates
Oligos, Primers, Probes and Genes
TaqMan Real-Time PCR Assays
Greener Products
See all product categories
Applications
Bioprocessing
Cell Culture and Transfection
Cell and Gene Therapy
Chromatography
Molecular Testing
Digital Solutions
DNA and RNA Extraction and Analysis
Spectroscopy, Elemental and Isotope Analysis
See all applications and techniques
Services
Integrated CDMO-CRO Services
CDMO Services
CRO Services
Custom Services
Enterprise Services
Financial and Leasing Services
Instrument Services
Lab Informatics
OEM and Commercial Supply
Training Services
Unity Lab Services
See all services
Help and Support
How to Order
Instrument Support
Learning Centers
Register for an Account
Technical Support Centers
See all help and support topics
Popular
TaqMan Real-Time PCR Assays
Antibodies
Oligos, Primers & Probes
GeneArt Gene Synthesis
Cell Culture Plastics
Contact Us
Quick Order
Order Status and Tracking
Documents and Certificates
Thermo Fisher Scientific Logo
Search
Thermo Fisher Scientific
Search All
Search
Search button
Search button
Close
Order Status
Quick Order
Sign in
Sign in
Don't have an account ?
Create Account
Account
Check Order Status
Aspire Member Program
Connect: Lab, Data, Apps
Custom Products & Projects
Services Central
This product has been added to your favorites list. Go to
My Favorites
System Message
OK
Cancel
LOADING
See other TP53 SIRNA Assays ›
Gene Symbol:
TP53
Gene Name:
tumor protein p53
Gene Aliases:
BCC7, LFS1, P53, TRP53
Chromosome Location:
Chr.17: 7668402 - 7687550 on Build GRCh38
UniGene ID:
Hs.437460
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID
2625
Purification
HPLC
Standard
In-Vivo Ready
Size
5 nmol
20 nmol
20 nmol
Cy3 | 20 nmol
FAM-MGB | 20 nmol
40 nmol
40 nmol
100 nmol
250 nmol
250 nmol
1 umol
10 umol
5 nmol
20 nmol
20 nmol
Cy3 | 20 nmol
FAM-MGB | 20 nmol
40 nmol
40 nmol
100 nmol
250 nmol
250 nmol
1 umol
10 umol
5 nmol
20 nmol
20 nmol
Cy3 | 20 nmol
FAM-MGB | 20 nmol
40 nmol
40 nmol
100 nmol
250 nmol
250 nmol
1 umol
10 umol
Availability
Inventoried
Catalog #
AM16708
Price
Your Price
Online offer:
Check your price ›
Add To Cart
Genomic Map
siRNA Details
More Information
Genomic Map
LOADING...
×
Back To Top
siRNA Details
Gene Symbol: TP53
Interrogated Sequence
Translated Protein
Targeted Exon(s)
siRNA Location
IMAGE Clone ID
RefSeq
NM_000546.5
NP_000537.3
10
1248
NM_001126112.2
NP_001119584.1
10
1245
NM_001126113.2
NP_001119585.1
11
1308
NM_001126114.2
NP_001119586.1
11
1381
NM_001126115.1
NP_001119587.1
6
928
NM_001126116.1
NP_001119588.1
7
1061
NM_001126117.1
NP_001119589.1
7
988
NM_001126118.1
NP_001119590.1
9
1365
NM_001276695.1
NP_001263624.1
11
1308
NM_001276696.1
NP_001263625.1
11
1381
NM_001276697.1
NP_001263626.1
6
928
NM_001276698.1
NP_001263627.1
7
1061
NM_001276699.1
NP_001263628.1
7
988
NM_001276760.1
NP_001263689.1
10
1248
NM_001276761.1
NP_001263690.1
10
1245
GenBank mRNA
AB082923.1
-
10
1109
AF307851.1
-
10
1181
AK223026.1
-
4
341
AK225838.1
-
10
1186
AK297462.1
-
11
1113
AK297927.1
-
11
1158
AK312568.1
-
10
1190
AM076970.1
-
9
1013
AY429684.1
-
9
1046
BC003596.1
-
10
1166
3544714
BT019622.1
-
9
1046
DQ186648.1
-
11
1311
DQ186649.1
-
11
1238
DQ186650.1
-
6
924
DQ186651.1
-
7
1057
DQ186652.1
-
7
984
DQ191317.1
-
10
1235
DQ263704.1
-
9
1046
DQ286964.1
-
10
1180
DQ648886.1
-
2
122
EF101867.1
-
9
1013
FJ207420.1
-
10
1181
JN214348.1
-
9
1091
JN601513.1
-
9
1046
JN601514.1
-
9
1046
JN601515.1
-
9
1046
JN601516.1
-
10
1020
JN900492.1
-
9
1354
JQ026207.1
-
9
1036
JQ026208.1
-
9
1041
JQ026209.1
-
9
1051
JQ026210.1
-
9
1041
JQ694049.1
-
9
1069
JQ694050.1
-
9
1069
JQ694051.1
-
9
1069
M14694.1
-
10
1171
M14695.1
-
10
1167
X01405.1
-
7
747
X02469.1
-
10
1181
X60011.1
-
9
1046
X60012.1
-
9
1046
X60013.1
-
9
1046
X60014.1
-
9
1046
X60015.1
-
9
1046
X60016.1
-
9
1046
X60017.1
-
9
1046
X60018.1
-
9
1046
X60019.1
-
9
1046
X60020.1
-
9
1046
Back To Top
More Information
Other Species Targeted
This siRNA also targets the following transcripts in Rat: XM_003749209.
Panther Classification:
Molecular Function -
P53-like transcription factor
Gene Ontology Categories:
Function(s)
Process(es)
negative regulation of transcription from RNA polymerase II promoter
DNA strand renaturation
base-excision repair
nucleotide-excision repair
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein complex assembly
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
ER overload response
cell cycle arrest
Ras protein signal transduction
multicellular organism development
cell aging
protein localization
cell proliferation
negative regulation of cell proliferation
determination of adult lifespan
response to X-ray
response to gamma radiation
positive regulation of gene expression
viral process
protein sumoylation
cell differentiation
negative regulation of cell growth
DNA damage response, signal transduction by p53 class mediator
positive regulation of histone deacetylation
chromatin assembly
mitotic G1 DNA damage checkpoint
positive regulation of protein oligomerization
cellular response to UV
cellular response to drug
cellular response to glucose starvation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
entrainment of circadian clock by photoperiod
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of neuron apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
response to antibiotic
positive regulation of protein export from nucleus
regulation of mitochondrial membrane permeability
negative regulation of fibroblast proliferation
circadian behavior
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of helicase activity
protein tetramerization
negative regulation of telomerase activity
positive regulation of thymocyte apoptotic process
positive regulation of cell cycle arrest
cellular response to hypoxia
cellular response to ionizing radiation
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of release of cytochrome c from mitochondria
replicative senescence
oxidative stress-induced premature senescence
intrinsic apoptotic signaling pathway
oligodendrocyte apoptotic process
positive regulation of execution phase of apoptosis
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
regulation of signal transduction by p53 class mediator
regulation of cell cycle G2/M phase transition
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
positive regulation of reactive oxygen species metabolic process
positive regulation of intrinsic apoptotic signaling pathway
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter sequence-specific DNA binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protease binding
p53 binding
DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
copper ion binding
protein binding
ATP binding
transcription factor binding
zinc ion binding
enzyme binding
protein kinase binding
protein phosphatase binding
receptor tyrosine kinase binding
ubiquitin protein ligase binding
histone acetyltransferase binding
identical protein binding
sequence-specific DNA binding
protein self-association
transcription regulatory region DNA binding
protein heterodimerization activity
protein N-terminus binding
chaperone binding
protein phosphatase 2A binding
Back To Top
Related Products
Anti-GAPDH, Mouse Monoclonal 6C5
Anti-β-Actin, Mouse Monoclonal AC-15
TaqMan
®
Gene Expression Cells-to-CT
™
Neon
™
Transfection System 100 µL Kit
Lipofectamine
™
RNAiMAX Transfection Reagent
Invivofectamine 2.0
Lipofectamine
™
2000 Transfection Reagent
Neon
™
Transfection System
AddToFavs result goes here(DO NOT DELETE ME!)
Close X
Your item
s have
has
been added!
Host server : magellan-search-green-7745c474b-b2rzg:80/100.66.78.226:80.
git-commit: c3c9db9cc82507548abdd0ae6a4ade3f81f66292
git-url: https://github.com/thermofisher/magellan-search
git-branch: release/2.20.0-2024.11.45-1.0