Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign in
Don't have an account ?
Create Account
Products
Antibodies
Cell Culture Media
Chemicals
Chromatography Columns and Cartridges
Lab Equipment
Lab Plasticware and Supplies
Microplates
Oligos, Primers, Probes and Genes
TaqMan Real-Time PCR Assays
Greener Products
See all product categories
Applications
Bioprocessing
Cell Culture and Transfection
Cell and Gene Therapy
Chromatography
Molecular Testing
Digital Solutions
DNA and RNA Extraction and Analysis
Spectroscopy, Elemental and Isotope Analysis
See all applications and techniques
Services
Integrated CDMO-CRO Services
CDMO Services
CRO Services
Custom Services
Enterprise Services
Financial and Leasing Services
Instrument Services
Lab Informatics
OEM and Commercial Supply
Training Services
Unity Lab Services
See all services
Help and Support
How to Order
Instrument Support
Learning Centers
Register for an Account
Technical Support Centers
See all help and support topics
Popular
TaqMan Real-Time PCR Assays
Antibodies
Oligos, Primers & Probes
GeneArt Gene Synthesis
Cell Culture Plastics
Contact Us
Quick Order
Order Status and Tracking
Documents and Certificates
Thermo Fisher Scientific Logo
Search
Thermo Fisher Scientific
Search All
Search
Search button
Search button
Close
Order Status
Quick Order
Sign in
Sign in
Don't have an account ?
Create Account
Account
Check Order Status
Aspire Member Program
Connect: Lab, Data, Apps
Custom Products & Projects
Services Central
This product has been added to your favorites list. Go to
My Favorites
System Message
OK
Cancel
LOADING
See other TP53 SIRNA Assays ›
Gene Symbol:
TP53
Gene Name:
tumor protein p53
Gene Aliases:
BCC7, LFS1, P53, TRP53
Chromosome Location:
Chr.17: 7668402 - 7687550 on Build GRCh38
UniGene ID:
Hs.437460
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID
s536422
Purification
HPLC
Standard
HPLC-IVR
Size
1 nmol
5 nmol
InVivo | 5 nmol
20 nmol
20 nmol
40 nmol
40 nmol
250 nmol
250 nmol
InVivo | 250 nmol
InVivo | 250 nmol
1 umol
1 umol
InVivo | 1 umol
InVivo | 1 umol
10 umol
10 umol
1 nmol
5 nmol
InVivo | 5 nmol
20 nmol
20 nmol
40 nmol
40 nmol
250 nmol
250 nmol
InVivo | 250 nmol
InVivo | 250 nmol
1 umol
1 umol
InVivo | 1 umol
InVivo | 1 umol
10 umol
10 umol
1 nmol
5 nmol
InVivo | 5 nmol
20 nmol
20 nmol
40 nmol
40 nmol
250 nmol
250 nmol
InVivo | 250 nmol
InVivo | 250 nmol
1 umol
1 umol
InVivo | 1 umol
InVivo | 1 umol
10 umol
10 umol
Availability
Inventoried
Catalog #
4392420
Price
Your Price
Online offer:
Check your price ›
Add To Cart
Genomic Map
siRNA Details
More Information
Genomic Map
LOADING...
×
Back To Top
siRNA Details
Gene Symbol: TP53
Interrogated Sequence
Translated Protein
Targeted Exon(s)
siRNA Location
IMAGE Clone ID
RefSeq
NM_000546.5
NP_000537.3
6
828
NM_001126112.2
NP_001119584.1
6
825
NM_001126113.2
NP_001119585.1
6
828
NM_001126114.2
NP_001119586.1
6
828
NM_001126115.1
NP_001119587.1
2
508
NM_001126116.1
NP_001119588.1
2
508
NM_001126117.1
NP_001119589.1
2
508
NM_001126118.1
NP_001119590.1
5
945
NM_001276695.1
NP_001263624.1
6
828
NM_001276696.1
NP_001263625.1
6
828
NM_001276697.1
NP_001263626.1
2
508
NM_001276698.1
NP_001263627.1
2
508
NM_001276699.1
NP_001263628.1
2
508
NM_001276760.1
NP_001263689.1
6
828
NM_001276761.1
NP_001263690.1
6
825
GenBank mRNA
AB082923.1
-
6
689
AF307851.1
-
6
761
AK225838.1
-
6
766
AK297462.1
-
7
693
AK297927.1
-
7
738
AK303277.1
-
5
884
AK312568.1
-
6
770
AM076970.1
-
5
593
AM076971.1
-
5
626
AM076972.1
-
5
626
AY429684.1
-
5
626
BC003596.1
-
6
746
3544714
BT019622.1
-
5
626
DQ186648.1
-
6
758
DQ186649.1
-
6
758
DQ186650.1
-
2
504
DQ186651.1
-
2
504
DQ186652.1
-
2
504
DQ191317.1
-
6
815
DQ263704.1
-
5
626
DQ286964.1
-
6
760
DQ648884.1
-
5
426
DQ648885.1
-
3
302
EF101867.1
-
5
593
EF101868.1
-
5
626
EF101869.1
-
5
626
FJ207420.1
-
6
761
JN214348.1
-
5
671
JN601513.1
-
5
626
JN601514.1
-
5
626
JN601515.1
-
5
626
JN601516.1
-
6
600
JN900492.1
-
5
934
JQ026207.1
-
5
616
JQ026208.1
-
5
621
JQ026209.1
-
5
626
JQ026210.1
-
5
626
JQ694049.1
-
5
649
JQ694050.1
-
5
649
JQ694051.1
-
5
649
KC820708.1
-
2
121
KC820709.1
-
2
121
KC820710.1
-
2
121
KC820711.1
-
2
121
KC820712.1
-
2
121
KC820713.1
-
2
121
KC820714.1
-
2
121
KC820715.1
-
2
121
KC820716.1
-
2
121
KC820717.1
-
2
121
KC820718.1
-
2
121
KC820719.1
-
2
121
KC820720.1
-
2
121
KC820721.1
-
2
121
KC820722.1
-
2
121
KC820723.1
-
2
121
KC820724.1
-
2
121
KC820725.1
-
2
121
KC820726.1
-
2
121
KC820727.1
-
2
121
KC820728.1
-
2
121
KC820729.1
-
2
121
KC820730.1
-
2
121
KC820731.1
-
2
121
KC820732.1
-
2
121
KC820733.1
-
2
121
KC820734.1
-
2
121
KC820735.1
-
2
121
KC820736.1
-
2
121
KC820737.1
-
2
121
KC820738.1
-
2
121
KC820739.1
-
2
121
KC820740.1
-
2
121
KC820741.1
-
2
121
KC820742.1
-
2
121
KC820743.1
-
2
121
KC820744.1
-
2
121
KC820745.1
-
2
121
KC820746.1
-
2
121
KC820747.1
-
2
121
KC820748.1
-
2
121
KC820749.1
-
2
121
KC820750.1
-
2
121
KC820751.1
-
2
121
KC820752.1
-
2
121
KC820753.1
-
2
121
KC820754.1
-
2
121
KC820755.1
-
2
121
KC820756.1
-
2
121
KC820757.1
-
2
121
KC820758.1
-
2
121
KC820760.1
-
2
121
KC820761.1
-
2
121
KC820762.1
-
2
121
KC820763.1
-
2
121
KC820764.1
-
2
121
KC820765.1
-
2
121
KC820766.1
-
2
121
KC820767.1
-
2
121
KC820768.1
-
2
121
KC820769.1
-
2
121
KC820770.1
-
2
121
KC820771.1
-
2
121
KC820772.1
-
2
121
KC820773.1
-
2
121
KC820774.1
-
2
121
KC820775.1
-
2
121
KC820776.1
-
2
121
KC820777.1
-
2
121
KC820778.1
-
2
121
KC820779.1
-
2
121
KC820780.1
-
2
121
KC820781.1
-
2
121
KC820782.1
-
2
121
KC820783.1
-
2
121
KC820784.1
-
2
121
KC820785.1
-
2
121
KC820786.1
-
2
121
M14694.1
-
6
751
M14695.1
-
6
747
X01405.1
-
3
327
X02469.1
-
6
761
X60010.1
-
5
625
X60011.1
-
5
626
X60012.1
-
5
626
X60013.1
-
5
626
X60014.1
-
5
626
X60015.1
-
5
626
X60016.1
-
5
626
X60017.1
-
5
626
X60018.1
-
5
626
X60019.1
-
5
626
X60020.1
-
5
626
Back To Top
More Information
Other Species Targeted
This siRNA also targets the following transcripts in Rat: XM_003749209.
Panther Classification:
Molecular Function -
P53-like transcription factor
Gene Ontology Categories:
Function(s)
Process(es)
negative regulation of transcription from RNA polymerase II promoter
DNA strand renaturation
base-excision repair
nucleotide-excision repair
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein complex assembly
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
ER overload response
cell cycle arrest
Ras protein signal transduction
multicellular organism development
cell aging
protein localization
cell proliferation
negative regulation of cell proliferation
determination of adult lifespan
response to X-ray
response to gamma radiation
positive regulation of gene expression
viral process
protein sumoylation
cell differentiation
negative regulation of cell growth
DNA damage response, signal transduction by p53 class mediator
positive regulation of histone deacetylation
chromatin assembly
mitotic G1 DNA damage checkpoint
positive regulation of protein oligomerization
cellular response to UV
cellular response to drug
cellular response to glucose starvation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
entrainment of circadian clock by photoperiod
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of neuron apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
response to antibiotic
positive regulation of protein export from nucleus
regulation of mitochondrial membrane permeability
negative regulation of fibroblast proliferation
circadian behavior
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of helicase activity
protein tetramerization
negative regulation of telomerase activity
positive regulation of thymocyte apoptotic process
positive regulation of cell cycle arrest
cellular response to hypoxia
cellular response to ionizing radiation
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of release of cytochrome c from mitochondria
replicative senescence
oxidative stress-induced premature senescence
intrinsic apoptotic signaling pathway
oligodendrocyte apoptotic process
positive regulation of execution phase of apoptosis
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
regulation of signal transduction by p53 class mediator
regulation of cell cycle G2/M phase transition
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
positive regulation of reactive oxygen species metabolic process
positive regulation of intrinsic apoptotic signaling pathway
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter sequence-specific DNA binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protease binding
p53 binding
DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
copper ion binding
protein binding
ATP binding
transcription factor binding
zinc ion binding
enzyme binding
protein kinase binding
protein phosphatase binding
receptor tyrosine kinase binding
ubiquitin protein ligase binding
histone acetyltransferase binding
identical protein binding
sequence-specific DNA binding
protein self-association
transcription regulatory region DNA binding
protein heterodimerization activity
protein N-terminus binding
chaperone binding
protein phosphatase 2A binding
Back To Top
Related Products
Anti-GAPDH, Mouse Monoclonal 6C5
Anti-β-Actin, Mouse Monoclonal AC-15
TaqMan
®
Gene Expression Cells-to-CT
™
Neon
™
Transfection System 100 µL Kit
Lipofectamine
™
RNAiMAX Transfection Reagent
Invivofectamine 2.0
Lipofectamine
™
2000 Transfection Reagent
Neon
™
Transfection System
AddToFavs result goes here(DO NOT DELETE ME!)
Close X
Your item
s have
has
been added!
Host server : magellan-search-green-7745c474b-6cdhd:80/100.66.78.96:80.
git-commit: c3c9db9cc82507548abdd0ae6a4ade3f81f66292
git-url: https://github.com/thermofisher/magellan-search
git-branch: release/2.20.0-2024.11.45-1.0