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Invitrogen
Human ABCA6 (aa 788-848) Control Fragment Recombinant Protein
Product Details
RP-107552
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
LEGQSTIEQDFEQVEMIRDSESLNEMELAHSSFSEMQTAVSDMGLWRMQVFAMARLRFLKL
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (61%), Rat (61%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66902. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The ATP-binding cassette (ABC) superfamily is comprised of transmembrane proteins involved in energy-dependent transport of a variety of substrates across membranes. ABCA6 is a 1,617 amino acid protein belonging to the ABC transporter family. ABCA6 is up-regulated during monocyte differentiation into macrophages, suggesting a role in macrophage lipid homeostasis. ABCA6 contains two ABC transporter domains and is expressed as three isoforms produced by alternative splicing. ABCA6 is present at highest levels in adult liver, with significant levels found in many adult tissues and fetal lung, kidney and liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ABC transporter ABCA6; ATP-binding cassette A6; ATP-binding cassette sub-family A member 6; ATP-binding cassette, sub-family A (ABC1), member 6
Gene Aliases: ABCA6; EST155051
UniProt ID: (Human) Q8N139
Entrez Gene ID: (Human) 23460
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