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Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83293. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1-acylglycerol-3-phosphate O-acyltransferase ABHD5; Abhydrolase domain-containing protein 5; aCGI58; CGI 58; CGI58 protein; Lipid droplet-binding protein CGI-58; MGC8731; truncated abhydrolase domain-containing protein 5
Gene Aliases: ABHD5; CDS; CGI-58; CGI58; IECN2; NCIE2
UniProt ID: (Human) B2R9K0
Entrez Gene ID: (Human) 51099
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